SYNLETT Journal

? In recent decades, nanocluster research has rapidly advanced. ? Though Cu nanoclusters are relatively new to the field, their use in chemical catalysis has expanded the potential applications of these materials. ? The reactivity of Cu nanoclusters is primarily determined by their precisely controlled structural architecture and surface-to-volume ratio, however, these factors are prone to change, significantly impacting their catalytic properties. ? Therefore, a comprehensive understanding of these parameters is crucial to guide future research efforts and develop new Cu nanoclusters with broader applications. ? Amit Pal,?Sourav Biswas,?Basudev Sahoo and?Yuichi Negishi present their Synpact on this area. ?? Read more here: https://lnkd.in/erqpv44g

?? New article-type alert! ? Ruben Martin,?Manuel van Gemmeren and?Debabrata Maiti present their opinion piece on the importance of data and why Perspectives have been added as a new type of manuscript in Synlett! ?? Read it here: https://lnkd.in/eQcK-rAN

?? Meet Laura Klink at the Chemiedozententagung in Braunschweig (17–19 March)! We’re excited that Laura Klink will be attending her first conference as part of Thieme’s Chemistry Journals Editorial Team! If you’re at #Chemiedozententagung, don’t miss the opportunity to connect with her. Laura is looking forward to meeting researchers, learning about exciting new work, and discussing publishing opportunities with Thieme Chemistry Journals. Be sure to say hello! ?????? #ThiemeChemistry #AcademicPublishing #ChemistryConference

? Catalytic asymmetric dearomatization reactions represent a versatile platform for constructing complex optically active three-dimensional molecules. ?? Liuzhen Hou,?Longqing Yang,?Xiaohua Liu,?Weidi Cao and?Xiaoming Feng present a visible-light-induced asymmetric dearomative [2+2] cycloaddition/ring-expansion reaction of indole derivatives with simple alkenes in the presence of a chiral?N,N′-dioxide/terbium complex. ?? This strategy provides access to a range of valuable cyclopenta[b]indoles, and its synthetic potential is further showcased through a gram-scale synthesis, potential bioactivity against human breast cancer, and further transformation into a yuehchukene analogue. ?? Read more here: https://lnkd.in/eAkRM9QY

? Carboxylic acids, a bench-stable, readily available, and structurally diverse class of compounds, represent ideal starting materials for organic synthesis. ? In their Synpacts article, Luca Mareen Denkler,?Meghana Aladahalli Shekar and?Ala Bunescu highlight an iron-catalyzed, decarboxylative, C(sp3)–O bond-forming reaction that takes place under mild, photocatalytic, base-free conditions using 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) derivatives as oxygenation reagents. ?? Read more here: https://lnkd.in/e_5EKyQU

?? Congratulations to the 2025 #WomenInChemistry Award winners: ?? Prof. Franziska Schoenebeck (RWTH Aachen University) – Academia ?? Dr. Dani Schultz (Merck) – Industry Franziska Schoenebeck has published prolifically wtih Thieme, particularly in SYNTHESIS Journal and SYNLETT Journal, so we value her support. In addition, she was the recipient of the 2024 Thieme-IUPAC prize! Dani Schultz has also made significant contributions to science, especially within process chemistry at Merck. Well done to both! ??

? This synpacts article by Nicolas Müller,?Ond?ej Ková?,?Alexander Rode,?Daniel Atzl and?Thomas Magauer outlines their synthetic endeavors towards the?Ganoderma?meroterpenoid ganoapplanin. ?? This natural product was isolated from a?Ganoderma?fungus in 2016 and was found to be an inhibitor for T-type voltage-gated calcium channels. ??? Their synthetic approach is based on a powerful intramolecular Giese cyclization/intermolecular aldol cascade to link the northern aromatic to the southern terpenoid fragment. ?? Read more here: https://lnkd.in/ePKcSuTe

?? Congratulations to the 2025 #WomenInChemistry Award winners: ?? Prof. Franziska Schoenebeck (RWTH Aachen University) – Academia ?? Dr. Dani Schultz (Merck) – Industry For the first time, the award (sponsored by Chemistry at Thieme) recognizes one outstanding female scientist from academia and industry. Dani's and Franziska's exceptional contributions to #OrganicSynthesis and #Catalysis are shaping the future of the field! ???? Learn more ?? https://brnw.ch/21wR7o7 The awards will be presented at #ESOC2025 in Copenhagen. ?? Join us in celebrating their achievements! #WomenInSTEM #OrganicChemistry #ScienceOfSynthesis

?? Published as part of our Natural Products and Bioactive Small Molecules series ?? Eight new 4,5-seco-abietane-type diterpenes, salpratones B–I, along with two analogues, featuring diverse 6/5/6, 6/6/6, 6/6/7, and 6/6/8 ring systems, were isolated from?Salvia prattii. ? Notably, salpratone B is the first example of a 4,5;13,14-bis-seco-abietane diterpene characteristic with a rare rearranged 6/5/6 tricyclic core skeleton. ?? Their structures were determined by comprehensive NMR spectroscopy, single-crystal X-ray diffraction, and electronic circular dichroism. ?? While salpratones B, E, F can weakly prolong the clotting times of human plasma in the activated partial thromboplastin time (APTT) assays with concentrations of 100 μM, showing no appreciable anticoagulant activities. ?? Read more here: https://lnkd.in/eAS5GuNv

?? The best poster presentation prize was announced at he 1st Meeting of Organic Chemistry of the Catalan Chemical Society (1RQO-SQC) ?? The winner was Carmen María Arenas Baeza. Congratulations!! ?? For more infromation see this link: https://lnkd.in/eHairbMB