CNSI Tech Centers

TECH CENTER ANNOUNCEMENT: UCLA’s NanoLab is expanding its capabilities with two cutting-edge direct-write lithography tools from Heidelberg Instruments: the DWL 66+ laser lithography system and the MLA 150 maskless aligner. These advanced instruments will enhance research across nanotechnology, microelectronics, quantum semiconductor materials, and more by enabling faster, more precise, and cost-effective patterning. Available in early 2025, these systems will serve researchers from UCLA, other academic institutions, and private tech companies. The DWL 66+ offers high-resolution, customizable pattern generation with features as small as 300 nm, while the MLA 150 enables maskless lithography down to 600 nm with automatic layer alignment. Both tools streamline the creation of intricate structures with increased precision and efficiency. Learn more: https://lnkd.in/gZUWssNX

The UCLA NanoLab at the CNSI Tech Centers has introduced the Thermo Fisher Scientific Verios 5 UC XHR, a powerful and user-friendly scanning electron microscope for high-resolution imaging and elemental analysis of conducting and nonconducting materials at the nanometer scale. Equipped with high-sensitivity detectors, energy dispersive X-ray spectroscopy, and automation features like FLASH fine-tuning and SmartAlign technology, the Verios 5 enables precise, efficient characterization with minimal user adjustments. Open to UCLA researchers, other universities, and industry labs, this advanced tool supports materials science, engineering, and medical research. Learn more on the NanoLab website: https://nanolab.ucla.edu/

The California NanoSystems Institute at UCLA has unveiled the advanced Krios G4 cryo-electron microscope—one of the first of its kind in the U.S.—offering nearly double the resolution and nine times the speed of its predecessor. This cutting-edge instrument—located at the Electron Imaging Center for NanoSystems within the CNSI Tech Centers—will enhance biomedical research, enable breakthroughs in fields like cancer and Alzheimer’s, and expand educational opportunities by integrating machine learning and AI into structural biology ?? Read the full announcement in the link below! https://lnkd.in/gyebhc7X

TECH CENTER ANNOUNCEMENT: The California NanoSystems Institute at UCLA has added two state-of-the-art scanning electron microscopes (SEMs) from Thermo Fisher Scientific—the Quanta 650 FEG and the Teneo LoVac—to its Electron Imaging Center for Nanosystems (EICN), part of the CNSI Tech Centers. These advanced instruments, available to both academic and industry researchers, offer exceptional resolution, flexibility, and automation for studying nanostructures, materials, and devices. The new tools enhance research capabilities across disciplines by providing unparalleled imaging clarity and specialized features like automated image stitching and advanced spectroscopy. Learn more in the link below: https://lnkd.in/gURNeemd

Step into the future of nanoscience! ?? On November 15th, the California NanoSystems Institute at UCLA hosted an open house, inviting researchers, students, and visitors to explore our six CNSI Tech Centers—launchpads for scientific breakthroughs that benefit both UCLA and the global research community. As part of the open house, guests toured our cutting-edge facilities, from #cryoEM imaging that reveals atomic structures to super-resolution microscopy capturing molecular activity in living cells. Attendees also explored our nanofabrication labs, where scientists manipulate matter on a scale thousands of times smaller than a human hair. Check out the photos below for highlights from the tours, and stay in touch with us for details about our next open house in 2025! Learn more about our technology centers here: https://lnkd.in/gRQh8f_Z

The California NanoSystems Institute at UCLA invites you to join us November 15th for a Technology Center Open House! Join researchers, post-docs, students and area stakeholders in learning about the CNSI’s six technology centers which provide UCLA and the greater scientific community with leading technologies, including high-throughput molecular screening to discover novel drug candidates, cryo-electron imaging to reveal atomic structures ranging from new materials to therapeutic targets, super-resolution light microscopy for examining the behavior of single molecules within cells, and nanofabrication facilities for observing and manipulating matter at the nanoscale. https://bit.ly/4dSavOK

Check out the video below to learn more about the?BioPACIFIC MIP Additive Manufacturing Facility and its state-of-the-art equipment, including the?Cellink BioX?and?LumenX DLP bioprinters, as well as the?SMaLL process?for multi-material 3D printing! The facility, located at UC Santa Barbara, provides cutting-edge resources for?rapid prototyping, advanced manufacturing, soft lithography, and 3D printing. With advanced technology like the?Carbon M2?and?Mono 3Z2?printers, it enables researchers to fabricate complex structures from?bio-derived monomers?tailored to specific applications. Learn more: https://lnkd.in/gy4hiR53

TECH CENTER ANNOUNCEMENT: Researchers at UCLA now have access to cutting-edge transfection technology with the newly available Fisher Scientific BTX Gemini X2 Electroporation System at the BioPACIFIC MIP Living Biofoundry, located at the California NanoSystems Institute at UCLA ?? This scalable, efficient, and versatile instrument can insert 96 distinct DNA/RNA constructs into various organisms in under 20 seconds, offering a powerful tool for advancements in gene editing, molecular biology, and regenerative medicine. Learn more in the link below: https://lnkd.in/gt-Vu4_5

Here's a great example of how an integrated suite of capabilities, including #confocal and #electronmicroscopy, enables researchers to leverage open-access labs for discovery in the California NanoSystems Institute at UCLA. Congrats to Manish Butte, Song Li, and the rest of the team UCLA who developed an implantable, biodegradable scaffold to enhance T-cell immunity while minimizing the toxicities of systemic therapies that could be a game-changer in the treatment of solid tumors!