Which is Better: Vegetarian (HPMC) or Gelatin Capsules? [Vol. 2]

Part Two: Health & Safety

Consumers are driving the discussion around their health products in terms of sustainability and safety as much as effectiveness. In this evolving landscape, the shift towards plant-based and vegetarian (HPMC) capsules in the industry is more than a trend – it is a necessity.?

The movement, however, is driven not only by ethical considerations, but also by science and more practical reasons like safety and product performance. This article will explore the key distinctions between vegetarian capsules and traditional gelatin capsules, and reasons why demand is rapidly shifting towards HPMC.

4. Non-Toxic & Non-Digestible

Hydroxypropyl methylcellulose (HPMC), commonly used in vegetarian capsules, is non-toxic and non-digestible. It simply passes through the body without adverse effects.?

On the other hand, studies show that animal-based gelatin may sometimes cause allergic reactions. These symptoms can include a tingly or itchy mouth, swelling of the lip, tongue, throat, or face — as well as vomiting, diarrhea, and cramping.

5. Lower Bacteria Growth

Lastly, HPMC capsules inherently possess a reduced tendency for bacteria proliferation. Animal-based materials, such as gelatin, are often more susceptible to bacterial and microbial growth due to the organic nature and proteins found in these materials.?

Studies suggest the bacteriological quality of gelatin is always in question. While extreme temperatures and pH conditions during the manufacturing process should ensure the sterility of the product, quality-control testing suggests bacteria may persist.

There have been reports of gram-positive and gram-negative contamination in the gelatin production process — which can then filter into the pharmaceuticals and food & beverage products with which it is formulated.?

This makes the choice of vegetarian capsules an added safety measure in capsule formulation, both in terms of long-term product shelf life and reducing potential risks to the consumer.

The choice between vegetarian and gelatin capsules should consider your consumer preference, product performance and sustainability standards. In summary, plant-based and vegetarian (HPMC) capsules provide the following advantages over traditional gelatin capsules:

• Enhanced Safety: They negate the potential risks of animal-related diseases
• Improved Health Compatibility: Being non-toxic and non-digestible, they align better with human health
• Sustainable Manufacturing: They're more sustainable for the environment, less ethically flawed, and better aligned with modern consumer demands
• Superior Performance: Their resilience in various storage conditions ensures product integrity

Vegetarian capsules embody the intersection of science, ethics, health, and environmental stewardship. The choice is practical, as well as strategic, to align with the evolving demands of consumers and regulators alike.

Read Part One: Ethics, Sustainability & Functionality >>

References

"Cellulose ethers in pharmaceuticals" by N. A. Peppas and J. J. Sahlin, in "Fiber Diffraction Methods," ACS Symposium Series, 1987