What's new this week from Drug Target Review...
Scientists at the Sylvester Comprehensive Cancer Center alongside collaborating organisations, have recently provided a new understanding of how glioblastoma cells mimic healthy human neurons. By using an AI algorithm, they are able to predict glioblastoma's most active kinase, and this insight could potentially lead therapies to prevent treatment resistance.
Dr David Kavanagh, shares how T-cell receptors offer window to the cell for a new class of cancer therapeutics. He further discusses how monoclonal antibodies are limited by their ability to only recognise tumour antigens expressed on the outside surface of a cell. Read more >>>
Lead researcher Dr Elena Rainero and her team have discovered a key metabolic process that cancer cells use to grow in a nutrient deprived environment, which in turn could be a new target. They have also investigated how tumours continue to grow despite this lack of nutrients.
Overtime, researchers have observed many quantifiable differences between diseased cells made from affected children and their gene-edited cells. In this new study, the researchers from Center for Regenerative Medicine have found a way to study the most common genetic cause of chILD using stem cells generated from each patient. Read more here.
TRENDING THIS WEEK
In this version of Beyond the lab, read more about RNA (ribonucleic acid) and how it plays a pivotal role in the intricate dance of cellular processes. Explore the latest breakthroughs in RNA-centric fields , and hear expert insights from Dr John Lewis, Sam Hasson, and many more. Download now to find out more.
Expand your knowledge by reading an overview of the DDR and innate immune pathway and describe Transcreener Assays and Assay Systems for key targets. Read more.
Download now for articles on A Microscopy Guide For Spatial Biology. This eBook delves into an understanding of how tissue landscapes with different microscopy techniques including multiplex imaging.
WHAT TO WATCH - get the date in your diary!
Have you registered for this innovative webinar with Eurofins DiscoverX? Don't miss out on the opportunity, register now to secure your place, and hear from Dr Jennifer Lin-Jones to learn more about:
WHAT TO READ
An in-depth Q&A with Dr Lev Becker, as he reveals how his company is directing research into neurtophil biology to the advantage of cancer patients that need it most. Download here to learn more.
Unique self-activating proteins for drug discovery have been found. Researchers have identified two unique proteins within N. fowleri – self-activating guanine nucleotide-hydrolysing proteins (G proteins) – that present novel targets for drug discovery. Find out more on their up-to-date work.
Read more on how researchers have devised a model to quantify cell shape and internal organisation. Susanne Rafelski, reveals details on their 200,000 database study on high-resolution, three-dimensional images of human induced pluripotent stem cells, to Drug Target Review.
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