What's New With PFAS This Week

What's New With PFAS This Week

In a typical week more than 500 peer reviewed PFAS related articles are published--below is a small sample of recent articles.

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Peer Reviewed Articles

Ahmad, A., et al. (2024). "Sorption and diffusion of per-polyfluoroalkyl substances (PFAS) in high-density polyethylene geomembranes." Waste Management 174: 15-23.

The objective of this study is to investigate the fate and transport of per-polyfluoroalkyl substances (PFAS) through a high-density polyethylene (HDPE) geomembrane (GM) that is commonly used in landfill composite liner systems. Tests were conducted to measure the sorption and diffusion of per-polyfluoroalkyl substances (PFAS) with varying number of carbons in chain and functional groups on HDPE GM. Perfluoroalkyl carboxyl acids (PFCAs), perfluoroalkyl sulphonic acids (PFSAs), alkyl-sulfonamidoacetic acids (FOSAAs), fluorotelomer sulfonic acids (FtSAs), alkane sulfonamides (FOSA) and ether carboxylic acids (Gen X) were investigated in this study.

?Link to article: Sorption and diffusion of per-polyfluoroalkyl substances (PFAS) in high-density polyethylene geomembranes - ScienceDirect

Aryal, P., et al. (2024). "Microfluidics in environmental analysis: advancements, challenges, and future prospects for rapid and efficient monitoring." Lab Chip.

Microfluidic devices have emerged as advantageous tools for detecting environmental contaminants due to their portability, ease of use, cost-effectiveness, and rapid response capabilities. These devices have wide-ranging applications in environmental monitoring of air, water, and soil matrices, and have also been applied to agricultural monitoring. Although several previous reviews have explored microfluidic devices' utility, this paper presents an up-to-date account of the latest advancements in this field for environmental monitoring, looking back at the past five years. In this review, we discuss devices for prominent contaminants such as heavy metals, pesticides, nutrients, microorganisms, per- and polyfluoroalkyl substances (PFAS), etc.

?Link to article: d3lc00871a ( rsc.org )

Averina, M., et al. (2024). "Early menarche and other endocrine disrupting effects of per- and polyfluoroalkyl substances (PFAS) in adolescents from Northern Norway. The Fit Futures study." Environmental Research 242.

?Background: Per- and polyfluoroalkyl substances (PFAS) comprise a large group of chemicals that are ubiquitous in the environment and include recognized persistent organic pollutants. The aim of this cross-sectional study was to investigate possible endocrine disrupting effects of different PFAS in adolescents. Methods: Serum concentrations of PFAS, thyroid, parathyroid and steroid hormones were measured in 921 adolescents aged 15-19 years in the Fit Futures study, Northern Norway. The questionnaire included data on selfreported age at menarche and puberty development score (PDS). Multiple linear and logistic regression analyses and principle component analyses (PCA) were used to assess associations of PFAS with hormones concentrations and puberty indices.

Link to article: Early menarche and other endocrine disrupting effects of per- and polyfluoroalkyl substances (PFAS) in adolescents from Northern Norway. The Fit Futures study - ScienceDirect

Biswas, S. and B. M. Wong (2024). "Beyond Conventional Density Functional Theory: Advanced Quantum Dynamical Methods for Understanding Degradation of Per- and Polyfluoroalkyl Substances." ACS ES T Eng 4(1): 96-104.

Computational chemistry methods, such as density functional theory (DFT), have now become more common in environmental research, particularly for simulating the degradation of per- and polyfluoroalkyl substances (PFAS). However, the vast majority of PFAS computational studies have focused on conventional DFT approaches that only probe static, time-independent properties of PFAS near stationary points on the potential energy surface. To demonstrate the rich mechanistic information that can be obtained from time-dependent quantum dynamics calculations, we highlight recent studies using these advanced techniques for probing PFAS systems. We briefly discuss recent applications ranging from ab initio molecular dynamics to DFT-based metadynamics and real-time time-dependent DFT for probing PFAS degradation in various reactive environments.

Link to article: pubs.acs.org/doi/pdf/10.1021/acsestengg.3c00216

Depuydt, S. and B. Van der Bruggen (2024). "Green Synthesis of Cation Exchange Membranes: A Review." Membranes (Basel) 14(1).

Cation exchange membranes (CEMs) play a significant role in the transition to a more sustainable/green society. They are important components for applications such as water electrolysis, artificial photosynthesis, electrodialysis and fuel cells. Their synthesis, however, is far from being sustainable, affecting safety, health and the environment. This review discusses and evaluates the possibilities of synthesizing CEMs that are more sustainable and green.

Link to article: Membranes | Free Full-Text | Green Synthesis of Cation Exchange Membranes: A Review ( mdpi.com )

Gewurtz, S. B., et al. (2024). "Per- and polyfluoroalkyl substances (PFAS) in Canadian municipal wastewater and biosolids: Recent patterns and time trends 2009 to 2021." Science of the Total Environment 912.

?The concentrations of per- and polyfluoroalkyl substances (PFAS) were determined in raw influent, final effluent, and treated biosolids at Canadian wastewater treatment plants (WWTPs) to evaluate the fate of PFAS through liquid and solids trains of typical treatment process types used in Canada and to assess time trends of PFAS in wastewater between 2009 and 2021. Data for 42 PFAS in samples collected from 27 WWTP across Canada were used to assess current concentrations and 48 WWTPs were included in the time trends analysis.

Link to article: Per- and polyfluoroalkyl substances (PFAS) in Canadian municipal wastewater and biosolids: Recent patterns and time trends 2009 to 2021 ( sciencedirectassets.com )

Golosovskaia, E., et al. (2024). "Studying mixture effects on uptake and tissue distribution of PFAS in zebrafish<i> (Danio</i><i> rerio)</i> using physiologically based kinetic (PBK) modelling." Science of the Total Environment 912.

Per- and polyfluoroalkyl substances (PFAS) are ubiquitously distributed in the aquatic environment. They include persistent, mobile, bioaccumulative, and toxic chemicals and it is therefore critical to increase our understanding on their adsorption, distribution, metabolism, excretion (ADME). The current study focused on uptake of seven emerging PFAS in zebrafish (Danio rerio) and their potential maternal transfer. In addition, we aimed at increasing our understanding on mixture effects on ADME by developing a physiologically based kinetic (PBK) model capable of handling co-exposure scenarios of any number of chemicals.

Link to article: Studying mixture effects on uptake and tissue distribution of PFAS in zebrafish ( Danio rerio ) using physiologically based kinetic (PBK) modelling ( sciencedirectassets.com )

Hamid, N., et al. (2024). "The untold story of PFAS alternatives: Insights into the occurrence, ecotoxicological impacts, and removal strategies in the aquatic environment." Water Res 250: 121044.

Due to increasing regulations on the production and consumption of legacy per- and polyfluoroalkyl substances (PFAS), the global use of PFAS substitutes increased tremendously, posing serious environmental risks owing to their bioaccumulation, toxicity, and lack of removal strategies. This review summarized the spatial distribution of alternative PFAS and their ecological risks in global freshwater and marine ecosystems. Further, toxicological effects of novel PFAS in various freshwater and marine species were highlighted. Moreover, degradation mechanisms for alternative PFAS removal from aquatic environments were compared and discussed.

?Link to article: The untold story of PFAS alternatives: Insights into the occurrence, ecotoxicological impacts, and removal strategies in the aquatic environment - ScienceDirect

Jiang, D. Q. Y. and T. L. Guo (2024). "Interaction between Per- and Polyfluorinated Substances (PFAS) and Acetaminophen in Disease Exacerbation-Focusing on Autism and the Gut-Liver-Brain Axis." Toxics 12(1).

?This review presents a new perspective on the exacerbation of autism spectrum disorder (ASD) by per- and polyfluoroalkyl substances (PFAS) through the gut-liver-brain axis. We have summarized evidence reported on the involvement of the gut microbiome and liver inflammation that led to the onset and exacerbation of ASD symptoms. As PFAS are toxicants that particularly target liver, this review has comprehensively explored the possible interaction between PFAS and acetaminophen, another liver toxicant, as the chemicals of interest for future toxicology research.

Link to article: Toxics | Free Full-Text | Interaction between Per- and Polyfluorinated Substances (PFAS) and Acetaminophen in Disease Exacerbation&mdash;Focusing on Autism and the Gut&ndash;Liver&ndash;Brain Axis ( mdpi.com )

Link, G. W., et al. (2024). "Per- and polyfluoroalkyl substances (PFAS) in final treated solids (Biosolids) from 190 Michigan wastewater treatment plants." Journal of Hazardous Materials 463.

Trends in concentration, distribution, and variability of per-and polyfluoroalkyl substances (PFAS) in biosolids are characterized using an extensive dataset of 350 samples from 190 wastewater treatment plants (WWTPs) across Michigan. All samples are comprised of final treated solids generated at the end of the wastewater treatment process.

Link to article: Per-and-Polyfluoroalkyl-Substances-PFAS-in-Final-Treated-Solids-Biosolids-from-190-Michigan-Wastewater-Treatment-Plants.pdf ( researchgate.net )

Liu, M., et al. (2024). "Hunting the missing fluorine in aqueous film-forming foams containing per-and polyfluoroalkyl substances." Journal of Hazardous Materials 464.

?Since aqueous film-forming foams (AFFFs) are major sources of per-and polyfluoroalkyl substances (PFAS), understanding the quantity and type of PFAS present in AFFFs is crucial for assessing environmental risk and remediation. We characterized 25 foams from Canada and Europe, including two non-AFFFs and two fluorine free AFFFs. We used liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) to identify novel PFAS, as well as total oxidizable precursor assays (TOP) and total organofluorine (TOF) measurements for comparison.

Link to article: Hunting the missing fluorine in aqueous film-forming foams containing per- and polyfluoroalkyl substances - ScienceDirect ?

Momo, H. D., et al. (2024). "Associations of per- and polyfluoroalkyl substances and nonalcoholic fatty liver disease in the United States adult population, 2003-2018." Environmental Epidemiology 8(1).

?Background:Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder worldwide and a leading cause of liver-related mortality. Prior studies have linked per- and polyfluoroalkyl substances (PFAS) exposure to liver dysfunction and alterations in metabolic pathways, but the extent of a PFAS-NAFLD relationship is unclear. Thus, the aim of the current study was to examine whether there were associations between PFAS exposures and NAFLD in the US adult population over a 16-year period.

?Link to article: Associations of per- and polyfluoroalkyl substances and nona... : Environmental Epidemiology ( lww.com )

Federal Register/ Federal Government

Federal Register :: Assistance to Firefighters Grant Program

FEMA 1/19

PFAS chemical exposure | ATSDR ( cdc.gov )

ATSDR 1/18

Data for Statewide Reconnaissance of Per- and Polyfluoroalkyl Substances in Rivers and Streams of Virginia, 2022-2023 | U.S. Geological Survey ( usgs.gov )

USGS 1/18

PFAS Weekly US State News

If you are tracking PFAS news, happenings and business development opportunities in a particular area, contact us to find out about PFAS Local [email protected]

3 Arizona water systems near Globe to receive funding for PFAS ( ktar.com )

KTAR News (Phoenix, AZ) 1/21

CDC urges more blood testing for PFAS chemicals | Becker's ( beckershospitalreview.com )

Becker’s Hospital Review 1/19

'Water is the new gold, and our gold is rotten': West Plains Water Coalition produces short film on unfolding PFAS contamination | The Spokesman-Review

The Spokesman-Review (Spokane, WA) 1/22

Defense Department to again target 'forever chemicals' contamination near Michigan military base | AP News

AP News (Ann Arbor, MI) 1/19

Addressing the hidden dangers of firefighting: Firefighter Cancer Awareness Month ( thespec.com )

The Hamilton Spectator (Hamilton, ON, Canada) 1/23

PFAS Reports -- Other Sources

PFAS Issues in the Cannabis Industry | Food Safety ( food-safety.com )

Food Safety Magazine 1/24

PFAS and Health ( mn.gov )

Minnesota Department of Health (January 2024)

West Plains PFAS - Washington State Department of Ecology

Washington Department of Ecology 1/22

PFAS: Navigating Materials of Concern in Life Science Packaging | Healthcare Packaging

Healthcare Packaging 1/23


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