What is happening in the shade of COVID-19?
Is it a war against a virus, or a war of analgesics? Strange theories are advancing. Some of them have totally forgotten the importance of scientific evidence, and some may also appear as a “conspiracy” theory. What COVID-19 has in common with analgesics?
In a moment of great confusion, it may happen that strange, or even extreme “conspiracy” theories appear on the horizon; e.g. the ones deriving from the video clip interviewing Bill Gates, where he reveals his ideas on the danger represented by viruses.
But this is not the topic of this text. Instead let’s discuss about the scientific interest of the Paolo Procacci Foundation (PPF): analgesics and pain patients. Remaining true to itself, something the PPF has always upheld, that is to focus and dedicate its energy towards the patients. Hence, it is acceptable that their fate is still of interest to us. Maybe you are asking yourself what COVID-19 and pain patients have in common. Unless you do so artfully, it`s rather difficult to find a clear link connecting these two topics.
A link has been found by French politics. In fact, a surprising sensational declaration has opened Pandora`s box. It happened a week ago, when the French Health Minister declared that the use of anti-inflammatory drugs may increase the risk of COVID-19. He also has declared that all the COVID-19 patients should use just paracetamol. Such “high level” declaration has immediately attracted the attention of important mass media. Le Figaro Science has published an article with a shocking title: “Coronavirus: alert on ibuprofen and other anti-inflammatories”. This news has gone “viral” (an appropriate use of the word in the current situation), in less than 24 hours. Also, it has found other corners of the “scientific community” in the form of a “Correspondence” published in Lancet Respir Med. We will not comment on the scientific value of this “Correspondence”, as its value still remains too far away to be demonstrated. For now, we will just focus on the declaration trying to demonise anti-inflammatory drugs, including NSAIDs.
What is the impact of such high-level communication on the general population, already afraid and dazed by the pandemic?
With all due respect for our public institutions, we have questioned ourselves on the consequences; e.g. what would be the reaction of chronic pain patients treated for years with NSAIDs, and now terrified by the potentiality that such a group of drugs may increase the risk of Coronavirus infection. Also, we have imagined the reaction of millions of headache patients each year using over the counter NSAIDs, and especially ibuprofen. A part for these reflections, the research spirit has prevailed. Our initial thought was the Minister had made such important declarations based on scientific evidence that we might not be aware of. A very accurate search on the major research databases did not reveal any data that could validate this hypothesis provided to the mass media.
For the entire week, we have followed with great attention recent developments from this media saga, and something very interesting has been observed. In the coming days we will share this material with all of you. Meanwhile, we would just appreciate your opinion on this topic, which is for sure of interest to Pain Physicians worldwide.
Medical-Legal Consulting
4 年It seems almost unreal: this irresponsible use of limited information to play into fears. I have found it disturbing over years to see the disregard of science in general, how science works and what constitutes evidence. The same seems to have happened with opioids. We are all trying to thread the needle with opioid addiction / overdoses on the one hand and safe, judicious opioid analgesia for functional gains on the other while we see many prescribers leaving patients high and dry. Overprescribing (which certainly has been the case) does not warrant compensatory underprescribing. More like a wrecking ball than a pendulum, I think. The same can be said for NSAIDs. Neither panaceas nor the source of all problems, these are tools our patients need to be wielded in sophisticated hands. Even expression of principles of those who came before can play into poor medical decision - Hippocrates: "First do no harm." No, we don't really do that - what we aim to do is to do less harm. There are harms with pain. There are harms with interventions. Thread the needle.
Senior charge nurse at King Hussein Cancer Foundation and Center
5 年We should believe in evidence based practice, especially now during the crisis. One thing is no rumors or fake news.
Assessore ai Servizi Sociali presso Comune di Erbusco
5 年No comment!!!! Only scientific evidences are relevant!
Medical Senior Consultant
5 年I can't believe that some of these fake and unscientific themes make it all the way up to WHO. I am very upset about all the fake and fiction like ideas, people are terrified. What can you bieve what are we doctors to do in case of fever and inflammation? Hold hands and put cold towels on the forehead. I believe many patients won't use ibuprofen now even if prescribed. Non compliance and increase of risks. Any false or dangerous news should be punished. Ask first is it true, is there evidence and is it relevant.