What is Applications of computers in pharmacy?To know more attend The 12th Digital Pharmaceutical Innovations Expo & Congress from Nov 15-18, 2023,
What is Applications of computers in pharmacy? ?To know more attend The 12th Digital Pharmaceutical Innovations Expo & Congress from Nov 15-18, 2023, Los Angeles, USA.
1.??Drug??information??storage??and??retrieval??system ? 1. medication information storage and retrieval system ? The development of computers made it simpler to find information about drugs, including pharmacological activity, side effects, toxicity, medication interactions, etc. for pharmacists. International data banks are available for retrieving medical information. Among the examples on hand are Excerpt from the middle, MEDLARS, Bitnet, bios is, and Ama/net.
When the possibilities of this cutting-edge technology are used to develop innovative teaching and learning strategies, the usage of the World Wide Web in the classroom becomes extremely advantageous. The interactive modules in this basic pharmacokinetic class enable the transmission of the course material in an engaging way, and the pharmacokinetic simulation exercises gave the students learning opportunities that couldn't be replicated by textbooks. Two significant benefits come with the introduction of multimodal computer simulations in clinical pharmacy.
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a It allows for earlier exposure to clinical patient management for students during their educational process.
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Large numbers of students can receive clinical training thanks to this outside of typical clinical practise venues. Since multimedia programmes can combine audio, video, and even full-motion video, it is possible to create realistic simulations of patient care. Students have the freedom to go at their own pace, go in the direction they choose, and repeat material as many times as they choose. Online medical videos are accessible.
APPLICATIONS OF COMPUTERS IN PHARMACY
1.??Drug??information??storage??and??retrieval??system????The??drug??information??about
pharmacological??actions??adverse??effects??toxicity??drug??interactions??etc.??is??necessary??for
pharmacist and this search has been simplified by the use of computers. ? For retrieval of medical
information international data banks are available example includes: available example includes:
a Excerpta medial b MEDLARS c Bitnet d Biosis e Ama/net
2. Teaching and Training
i. upkeep of patient billing records and census lists. In hospitals, computers are employed to manage patient record databases that are updated often to represent the current status of all patients. The data saved includes name, age, sex, weight, and height. Name, age, sex, weight, and height are among the data stored. Allergies, medical diagnosis of additional illnesses, recommended medications, and special remarks.
ii. Letter and label preparation
APPLICATIONS OF COMPUTERS IN PHARMACY
1.??Drug??information??storage??and??retrieval??system????The??drug??information??about
pharmacological??actions??adverse??effects??toxicity??drug??interactions??etc.??is??necessary??for
pharmacist and this search has been simplified by the use of computers. ? For retrieval of medical
information international data banks are available example includes: available example includes:
a Excerpta medial b MEDLARS c Bitnet d Biosis e Ama/net
2. Teaching and Training
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APPLICATIONS OF COMPUTERS IN PHARMACY
1.??Drug??information??storage??and??retrieval??system????The??drug??information??about
pharmacological??actions??adverse??effects??toxicity??drug??interactions??etc.??is??necessary??for
pharmacist and this search has been simplified by the use of computers. ? For retrieval of medical
information international data banks are available example includes: available example includes:
a Excerpta medial b MEDLARS c Bitnet d Biosis e Ama/net
2. Teaching and Training
iii. Computers are particularly helpful for drugstore maintenance, procurement, and inventory control in hospital pharmacies.
iv. The clinical pharmacist may utilise a computer to monitor therapeutic drug use, which is necessary when a medicine has a limited therapeutic window.
v. Drug dose schedules are calculated by computer programmes to meet the needs of each patient.
vi. In addition to this, drug interactions can be screened utilising tools like PADIS Pharmacy Automated Drug Interaction Screening and MEDIPHOR Monitoring and Evaluation of Drug Interactions by Pharmacy Oriented Reporting.
? This service should be offered by every nation either alone or as a part of a regional network.
?The service should comprise gathering, examining, assessing, indexing, and delivering drug information to healthcare professionals.
? Access to clinical trials, libraries, and research facilities is made possible.
?Access to libraries, research centres, and educational activities is made possible through this.
? Government authorities should assist drug and toxicity information centres.
?They demand personnel with clinical training and access to specialised assistance.
? Drug information services may occasionally be offered.
In collaboration with pharmacovigilance initiatives and toxicology services.
Independent drug information centres are a crucial part of national initiatives to encourage the responsible use of medications, according to the WHO.
? Pharmacists and other healthcare professionals frequently give the community drug information.
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? The following basic tools are needed for a centre:
? A centre must have the following essential tools: furniture, a communication medium, internet connectivity, a printer, a photocopier, and electronic information sources.
? Haryana Sirs, Chhattisgarh Raipur, Rajasthan Jaipur, Assam Dibrugarh, and Goa Panaji all now have drug information centres thanks to a partnership between the WHO India Country Office and the Karnataka State Pharmacy Council (KSPC).
? The hunt for novel, safe, and effective medications has gotten more complex and expensive. ? Discovering new drugs and developing them is a protracted, challenging process. ? New medications are occasionally discovered by mistake. ? More often than not, they are created as a result of a concerted attempt to find fresh approaches to treating human disease while simultaneously enhancing quality of life. ? Generally speaking, the computer-aided drug design technique has the capacity to meet both of these objectives and enhance process effectiveness.
? A few examples of computer-assisted methods are
a CADD for computer-aided drug design
b Computer-aided molecular design, abbreviated CAMD
c Computer-assisted molecular modelling CAMM
? Designing thymidylate synthetize inhibitors as anticancer medicines is one recent example of CADD. HIV protease inhibitors are created as antiviral drugs. Employing a model of the sweet taste receptors, finding new sweeteners. ?Computer graphics such as receptor mapping, crystallography, and molecular dynamics molecular docking with NMR Quantum mechanics, including SAR, QSAR, and others, are frequently employed
? Computerized molecular modelling can give scientists knowledge that is crucial for the mechanistic design of medications, such as the three-dimensional structure of molecules and their chemical and physical properties. Comparison of one molecule's structure with those of other, distinct ones??visualisation of the complex generated between various molecules prediction of the appearance of linked chemicals. ? Molecule modelling software like GROMACS and AMBER CHARMM is frequently utilised. ?For instance, software Arcane Amber Cham Finder ASP and Cham Office CS.
6.Applied Biopharmaceutics
6.Applied Biopharmaceutics
6.Applied Biopharmaceutics
6.Applied Biopharmaceutics6.Applied Biopharmaceutics
6.Applied Biopharmaceutics
Pharmacokinetics is the study of how drugs and their metabolites change over time in the body's tissues, fluids, and excretions. ? Modern computer software programmes make it possible to quickly solve challenging pharmacokinetic equations and represent pharmacokinetic processes. Computer software is also utilised for the creation of experimental study designs. Computers ease laborious calculations.??Pharmacokinetic model simulation and projection or prediction of drug action statistical data treatment data manipulation graphic display of data
? Computer-aided pharmacokinetic/pharmacodynamics approaches are frequently used to quantify drug disposition and pharmacological effects, study exposure-response correlations, and forecast safety and efficacy results. ? Some pharmacokinetic software examples are Multiport Kinetics PK Solutions, Pharmed Madcap, ADAPT II NONMEM SAAM30, and CONSAM Boomer.
? A good pharmacokinetic programme or piece of software should: 1. Offer age and weight checks, lab value checks, etc. 2. Compare results to normative kinetics values and alert of +/- 2 standard deviations.??3. P
Assess the ability to store data and access it whenever necessary.??4. Give all ages the proper amount of flexibility with equations. 4. Give all ages the right amount of flexibility in equations. 5. Provide interoperability with a variety of printers.??4. be simple to understand and use.??5. Modify parameters based on liver or kidney function. 6. Feel confident in your professional judgement.
? Computer applications include handling data, processing it, storing it, searching it, and displaying it. ?Graphical data from the analysis of pharmaceuticals, pesticides, herbal extracts, etc. are produced as a spectrum with a number of peaks. ? Using library systems provided in the software of the analytical equipment (HPLC, HPTLC, GLC, MS, IR, etc.), the computer compares the spectrum of the given sample with the spectrum of a pure substance.
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The use of these tools for the analysis and interpretation of various types of biological data.
Everyday bioinformatics is done with sequence search programs like Blast sequence analysis
programs like the EMBOSS and Staden packages structure prediction programs like Threader or
PHD or molecular imaging/ modeling programs like RasMol
? Knowledge and a deeper understanding of manufacturing processes, product design methodologies, and manufacturing system design methodologies are necessary for successful manufacturing. ? There are numerous computer tools available for the production of pharmaceutical items and bulk medications. ? CAM software’s for computer-aided manufacturing are frequently product-focused. ? Spreadsheet software has been shown to be helpful for cost estimation, economic analysis, and material and energy balancing. ? Commercial flow sheet programmes include IPES by Union Carbide, COPE by Exxon, COPES by Du Pont, and COPE by Exxon.
? Bioinformatics is the application of a wide range of mathematical, statistical, biochemical, physicochemical, and computational techniques to the analysis of biological data. Bioinformatics is the fusion of biology and information technology. ? Essentially, bioinformatics consists of three parts:??the development of databases that enable the management and storage of massive biological data collections.?The creation of algorithms and statistics to identify associations between individuals in massive data sets.
Using these technologies to analyse and understand different kinds of biological data. The common tools used in bioinformatics are sequence search programmes like Blast, sequence analysis programmes like the EMBOSS and Staten packages, and molecular imaging/modelling programmes like Ramos.
? Data and Knowledge-Discovery??Mining is the automatic search for patterns in vast volumes of data using methods like classification association rule mining clustering etc. ? The global biopharmaceutical industry makes extensive use of significant data gleaned from various data mining approaches, including:??illness profile databases with annotations. Molecular mechanisms at play in terrible human diseases. QSAR stands for quantitative structure activity relationship. precise chemical compositions of compound combinatorial libraries. Results of novel molecule clinical studies.
? Computerized neural networks A significant area of medical study today is ANN. ? At the moment, the focus of study is primarily on simulating human body parts and diagnosing disorders using various scans, such as cardiograms, CAT scans, ultrasonic scans, etc. Experimental modelling of the human cardiovascular system uses neural networks. ? By creating a model of a person's cardiovascular system and comparing it to the patient's real-time physiological parameters, a diagnosis can be made.
12. e-Health
? E-Health is the use of electronic technology for information exchange, social engagement, and decision-support related to health. E-Health is a large and rapidly expanding sector that makes use of new technology, particularly the Internet and telephones. ? NIS Direct is an example of a modern telemedicine programme that has been expanded to offer advice services to the entire nation. ? Nurse-run clinics are now taking the role of traditional hospitals. ? The nurses speak with the patient, compile all the data on a computer, and then send this "electronic patient record" to an expert.
? Specialist reviews the file and uses his computer to send a report back to the nurse. This may include images, X-rays, ECGs, or text. ? She can discuss how to treat an injury via videoconference. ? Access to knowledge should be available to everyone, regardless of location, to facilitate equitable service delivery. ? Having access to reputable health information via the Internet, digital TV, and multimedia kiosks will enable us all to maintain better health.
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