Weekly Research News Digest
This newsletter is designed to share with you research news in various fields where applications of gene sequencing can be found. It will share research findings from Novogene’s customers. By sharing insights from the most prestigious research teams, it is intended to call your attention to the latest applications of sequencing in life sciences and biomedical research and inspire your research.
Welcome to the Weekly Research News Digest. In the?five articles?featured this week, researchers combined genomic, transcriptomic, and metabolomic technologies to explore the genomic characteristics and environmental adaptability of modern crops. These studies not only deepen our understanding of crop genetics and their interaction with the environment,?but also provide valuable insights for the development of more resilient and productive agricultural practices.
Unraveling Structural Variations in Soybean: Insights from a?High-Quality Genome of NDD2
Soybean is crucial for protein and oil production?and?the study of structural variations (SVs) is essential for its improvement. Researchers from Hebei Agricultural University and Novogene jointly assembled a?high-quality genome of the modern cultivar Nongdadou2 (NDD2),?identified 25,814 SV–gene pairs?by comparing it with 29 previously reported genomes, and?validated?13 private SVs?specific to NDD2?through deep resequencing of 547 accessions. They revealed?significant associations between 6,013 SVs and 22 traits?related to yield and seed quality and identified 1,761 SVs that affect genes or regulatory regions. This study enhances our?understanding of the roles of SVs in soybean improvement, providing valuable genomic resources.
Enhancing Soil Carbon Retention through Plant Diversity in Agricultural Systems
The expansion and intensification of agriculture has resulted in?soil carbon loss, underscoring the need for sustainable practices to mitigate climate change. Researchers from Switzerland, Finland, China, and France conducted a large field trial?in which a diversity gradient was realized by?intercropping barley with undersown species?which ranged?from one to eight. They found that increased?plant diversity enhanced positive associations within the rhizosphere soil microbial community, leading to?improved?community?carbon use efficiency. These findings suggest that promoting plant diversity in agricultural systems can effectively boost soil carbon retention.
Unraveling Drought Resistance Mechanisms in Tomatoes: The Role of BBX18 and APX1
The role of?B-box zinc finger proteins (BBX)?in crop drought tolerance has been poorly understood. A recent study published in Nature Communications?identified a natural allele of BBX18 (BBX18TT)?that codes a truncated protein at the C-terminus. BBX18TT can be found in most?modern cultivated tomatoes?which are more sensitive to drought,?whereas?BBX18CC allele is found in?most?wild tomato germplasms?which exhibited greater drought tolerance. The study showed that knocking out BBX18 improves drought tolerance and identified ascorbate peroxidase 1 (APX1) as a positive regulator?of drought resistance?whose expression is suppressed by BBX18. This research offers?insights into the molecular mechanisms of drought resistance modulated by?the BBX18-APX1 pathway in plants.
Enhancing Peanut Growth and Yield under Salinity Stress through Graphene Oxide Priming
While graphene oxide (GO)?is?increasingly recognized as a valuable nanomaterial for?agriculture, its?effects on seed priming for salinity tolerance and crop yield?remain unclear. Researchers from Hong Kong and Qingdao utilized physiological assessments, in combination with transcriptomics and metabolomics,?to investigate the impact of treating peanut seeds with 400 mg L?1 GO under both pot-grown?and field-grown?conditions. The results showed that GO-primed seeds demonstrated higher germination rates?in seed germination stage. During seeding stage, GO priming?enhanced growth under salinity stress.?At maturity, GO priming resulted in an average increase of 12.91% in peanut pod yield compared to the non-primed control.?These findings indicate that GO significantly improves seed germination, alleviates salinity stress, and increases peanut pod yield by modulating various physiological processes.
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Unraveling Cold-Induced Lignification in Red-Fleshed Loquat: The Role of EjXND1 and DNA Methylation
Lignin is essential for plant growth and stress resistance but adversely affects fruit quality, particularly in temperature-sensitive red-fleshed loquat, which exhibits cold-induced lignification. Researchers from Zhejiang University explored the mechanism that regulates cold-induced lignification in loquat fruit. They?identified the?Xylem NAC Domain?transcription factor EjXND1 as a repressor of lignification, which interacts with EjHB1 to inhibit the activation of EjPRX12 promoter. They showed that the methylation level of one highly methylated region in the promoter of EjXDN1 is negatively associated with EjXND1 expression.?Overall, EjXND1 is involved?in modified Low Temperature Conditioning (mLTC) treatment, which?mitigates cold-induced lignification in loquat fruit by regulating the EjHB1-EjPRX12 module.?Additionally, the regulation of EjXND1 is influenced by changes in DNA methylation levels in its promoter.
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About Novogene
Novogene specializes in the application of advanced molecular biotechnology and high-performance computing in the research fields of life science and human health. Established in March 2011, Novogene strives to become a global leader in providing genetic science services and technology products. Novogene has set up operations and laboratories in the United States, the United Kingdom, Netherlands, Germany, as well as in China, Singapore and Japan.
Novogene has served over 7,300 global customers, covering 90 countries and regions across 6 continents. It has cooperated extensively with many academic institutions and completed several advanced-level, international genomics research projects. By 2023, Novogene has co-published and/or been acknowledged in more than 22,850 articles in Science Citation Index, with an accumulative impact factor of more than 148,250.
Novogene's partners are worldwide and include more than 4,200 scienti?c research institutions and universities, more than 680 hospitals and over 2,400 pharmaceutical and agricultural enterprises. Currently, Novogene has obtained 425 software copyrights and 76 patents.
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