Visualization of mitochondrial DNA in living cells with super-resolution microscopy using thiophene-based terpyridine Zn(II) complexes

Visualization of mitochondrial DNA in living cells with super-resolution microscopy using thiophene-based terpyridine Zn(II) complexes

Visualization of mitochondrial DNA in living cells with super-resolution microscopy using thiophene-based terpyridine Zn(II) complexes

Yu Shen et al

10.1039/C8CC06276E

We present a thiophene-based terpyridine Zn(II) complex (namely LC) which could specifically target live cell mitochondria via binding with mitochondrial DNA (mtDNA). Due to its high biocompatibility, red emission and photo-stability, mtDNA distribution within mitochondrial cristae and inner matrix in living cells was successfully visualized using stimulated emission depletion (STED) nanoscopy with unprecedented resolution.

hi, very interesting. ?Can you please send me the full text as this might be of huge help for research in my lab? if possible please mail me at [email protected]. Thank you?

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