Usefulness of pepsin saliva measurement for the detection of primary burning mouth syndrome related to reflux

Examining the diagnostic utility of salivary pepsin tests in identifying laryngopharyngeal reflux (LPR) among primary burning mouth syndrome (BMS) patients, the study establishes the significance of the pepsin test in LPR detection for individuals with BMS. Those with elevated salivary pepsin levels exhibited more pronounced burning mouth symptoms. This underscores the value of the pepsin test as a diagnostic tool for identifying LPR in the context of primary BMS, providing insights into the relationship between salivary pepsin levels and symptom severity.