Urolithin A research opens door to osteoarthritis relief

Supplementing with urolithin A can improves mitochondrial health and reduce joint cartilage damage, new study shows.

Scientists at Amazentis and Scripps Research have shown that as well as alleviating pain in osteoarthritis sufferers, urolithin A supplementation can improve mobility as it has a beneficial effect on the structural damage osteoarthritis causes.

My take on this: Osteoarthritis is one of the most common types of arthritis and it occurs when the protective cartilage that cushions and protects the ends of the bones wears down. The risk of osteoarthritis increases with age, and is more common in women than in men – and there is currently no cure. Instead, those suffering with osteoarthritis manage the condition with exercise, weight loss, supportive devices, medications and, potentially, surgery if other options do not work.

Now new research indicates a back-to-basics approach could prove to be a winning strategy; improving mitochondrial health through urolithin A supplementation could help to reduce osteoarthritis damage and offer a welcome relief from joint pain.

The research team published pre-clinical results from a new study in Aging Cell, reporting on the joint health benefits of gut microbiome postbiotic urolithin A. They noted that for the first time a compound – Amazentis’ proprietary urolithin A supplement Mitopure – has been shown to improve mitochondrial health in an experimental model of osteoarthritis (OA).

Results showed significantly improved mitochondrial health in human cartilage cells which had been taken from both healthy and osteoarthritic knee joints. Supplementing with Mitopure for eight weeks protected against osteoarthritis disease progression in the experimental model.

Read the full article HERE.

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