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WO2021240275 - REAL-TIME METHOD OF BIO BIG DATA AUTOMATIC COLLECTION FOR PERSONALIZED LIFESPAN PREDICTION

Real-time method of bio big data automatic collection for personalized lifespan prediction & in-time severe diseases prevention with AI reporting system. Particularly, the present system includes at least one wearable and invention of one multi biomaterial portable container.

In operation, the present system tracks in real-time vital biodata of 400+ parameters.

Related Patent aka #Patentfamily documentsEP4147111?US17923678?PH12022553264?RU2023102967

1. A prediction system to assess life expectancy and a plurality of health parameter factors, said prediction system comprising:

a monitoring module configured to monitor said plurality of health parameter factors;

an assessment module configured as a neural network trained on data retrieved from a first database storing said plurality of health parameter factors from many individuals;

an evaluation module configured to evaluate human data training sample to draw conclusions based on a data set of a large number of people and summarizing at least one characteristic from said human data training sample;

a second stage module configured to develop a trained neural network and said trained neural network is a network that analyzes a plurality of historical data of an individual and group of individuals with same parameters; and

a generation module configured to provide output data and said output data is a human health assessment factor that is directly related to life expectancy of an individual;

wherein said human data training sample is selected from a plurality of input parameters obtained from at least one medical record, at least one wearable device worn by an individual, surveys, questionnaires and the like and said plurality of input parameters are stored in said first database.

2. The prediction system as claimed in claim 1 , wherein said trained neural network take into account a plurality of time-periods of life that affect both positively and negatively prognosis of life expectancy of said individual.

3. The prediction system as claimed in claim 1 , wherein said human health assessment factor is a combination of values obtained from test data of said individual and group of individuals with same parameters and at least one functional characteristic of each individual body.

4. The prediction system as claimed in claim 1 , wherein said plurality of health parameter factors are selected from at least one or in a combination from height, weight, age, gender, nutrition, physical activity level, nature of work, at least one geographical location, nationality, environmental conditions, stress level, genetic characteristics, diseases and the like of each individual.

5. The prediction system as claimed in claim 1 , wherein said evaluation module further comprises:

a first stage evaluation sub-module configured to instantly evaluate human data obtained at a particular point in time wherein a data set is of a large number of people, and summarizing a plurality of characteristics of people from said training sample; a second stage evaluation sub-module configured to develop a historical data neural network that analyzes historical data of said individual and group of individuals with similar parameters and wherein said historical data neural network is trained with a large amount of data over a long period of time by selecting at least one architecture of a neural network;

a third stage evaluation sub-module configured to recognize a large number of patterns from a plurality of input parameters to evaluate individual relationship between a plurality of person’s life and their respective health level;

wherein at least one or in combination of a personalized network parameters are selected from a plurality of genetic characteristics, current physical condition of the body, blood parameters, nutrition, and psycho emotional state of a person to determine accurate forecast for said individual.

6. The prediction system as claimed in claim 5, wherein said third stage evaluation sub-module further configured to form a core network and said core network is trained on a large data sample and subsequently said core network is adjusted for a specific individual by training said core network on said specific individual for a significant period of time.

7. The prediction system as claimed in claim 1 , wherein said trained neural network is trained using one or more algorithms comprising stochastic gradient descent optimizer, adaptive moment estimation optimization and root mean square propagation optimization.

8. The prediction system as claimed in claim 1 , wherein said prediction system further comprises:

a server configured to send a request to an artificial Intelligence (Al) engine module to retrieve a list of required parameters for permanent tracking of at least one or more upcoming diseases, which can shorten life dramatically of said individual and said artificial Intelligence (Al) engine module configured to structure received personal datasets of multiple individuals and form a user digital profile based on matches received from at least one user personal dataset with multiple datasets of general population received from multiple databases;

a recommendation module configured to provide personal severe diseases prevention recommendations; and

a report module configured to generate a disease risk report;

wherein said list of required parameters are real-time vital biodata of individuals and wherein artificial Intelligence (Al) engine module is configured to extract needed data from unstructured data.

9. The prediction system as claimed in claim 8, wherein said list of required parameters are split into an offline permanent tracking category and an online permanent tracking category.

10. The prediction system as claimed in claim 8, wherein said prediction system further comprises at least one smart wearable which contains at least one sensor to record physical properties, include anyone or combination of blood pressure on both hands (morning and night), heart rate variability, resting heart rate, V02max (direct measurement or Cooper test score), waist circumferences, common diseases (incl. depression, anxiety, cyberchondria, etc.), prescribed medications, nutritional supplements, entheogenic, recreational, performance enhancing and other medicines, movement data and sleep mode, mood and mental performance self-esteem, libido, body temperature, lung function, blood glucose, various active motion tests, outside temperature, humidity level, illumination level, electromagnetic fields, ionizing radiation & others from the body online and other physical and biodata, and at least one interface with a network capable of utilizing the information obtained from said at least one sensor.

11. The prediction system as claimed in claim 8, wherein said list of required parameters comprises age, sex, height, nationality, thigh/neck circumferences, Raffier-Dickson index for measuring aerobic endurance, reaction time test results, hand strength, Strange and Genchi tests, high frequency auditory test, visual acuity check orthostatic blood pressure restoration test, ECG, EEG, Pwv, hands-Free test, breath holding time after deep exhalation, and flexibility tests.

12. A method for predicting and assessing life expectancy, said method comprising:

monitoring a plurality of health parameter factors and assessing a neural network trained on data retrieved from a first database storing said plurality of health parameter factors from many individuals;

evaluating human data training sample to draw conclusions based on a data set of a large number of people and summarizing at least one characteristic from said human data training sample;

developing a trained neural network and said trained neural network is a network that analyzes a plurality of historical data of an individual and group of individuals with same parameters; and

generating output data and said output data is a human health assessment factor that is directly related to life expectancy of each individual; wherein said human data training sample is selected from a plurality of input parameters obtained from at least one medical record, at least one wearable device worn by an individual, surveys, questionnaires, manual input and the like and said plurality of input parameters are stored in said first database; and

wherein said trained neural network take into account a plurality of time-periods of life that affect both positively and negatively prognosis of life expectancy of said individual.

13. The method as claimed in claim 12, wherein said method further comprising the steps of:

retrieving a list of required parameters for permanent tracking of at least one or more upcoming diseases, which can shorten life dramatically of said individual;

structuring received personal datasets of multiple individuals and forming a user digital profile based on matches received from at least one user personal dataset with multiple datasets of general population received from multiple databases by artificial Intelligence (Al) engine module;

providing personal severe diseases prevention recommendations to said individual and generating a disease risk report;

wherein said list of required parameters are real-time vital biodata of individuals and wherein artificial Intelligence (Al) engine module is configured to extract needed data from unstructured data.

14. The method as claimed in claim 13, wherein said evaluating human data training sample step further comprising the steps of:

instantly evaluating human data obtained at a particular point in time wherein a data set is of a large number of people, and summarizing a plurality of characteristics of people from said training sample;

developing a historical data neural network that analyzes historical data of said individual and wherein said historical data neural network is trained with a large amount of data over a long period of time by selecting at least one architecture of a neural network;

recognizing a large number of patterns from a plurality of input parameters to evaluate individual relationship between a plurality of person’s life and their respective health level;

wherein at least one or in combination of a personalized network parameters are selected from a plurality of genetic characteristics, current physical condition of the body, blood parameters, nutrition, environment, behavior and psycho emotional state of a person to determine accurate forecast for said individual.

15. The method as claimed in claim 14, wherein a core network is formed and said core network is trained on a large data sample and subsequently said core network is adjusted for a specific individual by training said core network on said specific individual for a significant period of time.

16. The method as claimed in claim 12, wherein said human health assessment factor is a combination of values obtained from test data of said individual and at least one functional characteristic of said individual body.

17. The method as claimed in claim 12, wherein said plurality of health parameter factors are selected from at least one or in a combination from height, weight, age, gender, nutrition, physical activity level, nature of work, at least one geographical location, nationality, environmental conditions, stress level, genetic characteristics, diseases and the like of each individual.

18. The method as claimed in claim 12, wherein said trained neural network is trained using one or more algorithms comprising stochastic gradient descent optimizer, adaptive moment estimation optimization and root mean square propagation optimization & other.

19. The method as claimed in claim 12, wherein said method further comprises the steps of recording physical properties of said individual include anyone or combination of blood pressure on both hands (morning and night), heart rate variability, resting heart rate, V02max (direct measurement or Cooper test score), waist circumferences, common diseases (incl. depression, anxiety, cyberchondria, etc.), prescribed medications, nutritional supplements, entheogenic, recreational, performance enhancing and other medicines, movement data and sleep mode, mood and mental performance self-esteem, libido, body temperature, lung function, blood glucose, various active motion tests, outside temperature, humidity level, illumination level, electromagnetic fields, ionizing radiation & others from the body online and other physical and biodata, and at least one interface with a network capable of utilizing the information obtained from at least one sensor mounted on at least one smart wearable or portable.

20. The method as claimed in claim 12, wherein said list of required parameters comprises age, sex, height, nationality, thigh/neck circumferences, Raffier-Dickson

index for measuring aerobic endurance, reaction time test results, hand strength, Strange and Genchi tests, high frequency auditory test, visual acuity check orthostatic blood pressure restoration test, ECG, EEG, Pwv, hands-Free test, breath holding time after deep exhalation, and flexibility tests.

[0074] Accordingly, the present invention has a number of advantages. The present system is a 4P Medicine system - Prevention, Prediction, Participatory, Personalized. The present invention goal is to catch the “butterfly effect” of each person’s life trajectory, when it is early to make necessary changes for these people so they can live 20+ active and happy years without limitations. Moreover, the present instant

invention has the technical effect of providing personal and national interest solutions to everyone, each nation and region. By tracking top 20 severe diseases at the onset aka earliest known stages, the present invention is able to increase longevity of individuals and extend their lifespan. Further, early analysis saves money on expensive treatments, when severe disease is already in progress.

[0075] It is the object of the present invention, to deploy systems, health monitoring modules where the data can be analysed using artificial intelligence (Al) algorithms and the like. In other words, the data can be analysed using supervised learning, support vector network, machine learning, Al and the like. In some embodiments, algorithms and rules are used by machine learning to analyse the output of the system and provide various types of information for use in a clinical environment. For example, the data may be used for diagnoses, testing and teaching in some embodiments. Machine learning algorithms and Al backed reports in lifespan predictions are only in the beginning of its evolution.

[0076] Moreover, the present invention is monitoring more than 20+ parameters that current real-time online trackers can monitor, with health status & generating recommendation reports. There are no portable containers, which can collect distantly various types of biomaterials in one container and then to have biomaterial to be transcript for 400+ parameters, which can safely store biomaterials inside of the container & being brought in-time to the special lab.

[0077] While the present invention has been described in terms of particular embodiments and applications, in both summarized and detailed forms, it is not intended that these descriptions in any way limit its scope to any such embodiments and applications, and it will be understood that many substitutions, changes and variations in the described embodiments, applications and details of the method and system illustrated herein and of their operation can be made by those skilled in the art without departing from the spirit of this invention.