The Top 10 Biomarkers That You Should Know: Do not Miss These Early Disease Detection Clues!

Early detection is crucial when it comes to treating diseases. The earlier a disease is detected, the greater the chances of successful treatment. That's where biomarkers come in. Biomarkers are measurable indicators of biological processes that can be used to identify the presence of a disease or monitor its progression. In this article, we'll explore 10 biomarkers that are particularly useful for early disease detection.

PSA (Prostate-Specific Antigen):PSA is a protein produced by the prostate gland. Elevated levels of PSA in the blood can indicate the presence of prostate cancer. PSA testing is widely used for the early detection of prostate cancer, although its use has been controversial due to the risk of over diagnosis and overtreatment.

CA-125 (Cancer Antigen 125): CA-125 is a protein that is elevated in the blood of some women with ovarian cancer. CA-125 testing is not recommended for general population screening, but it may be used in certain high-risk populations to aid in early detection.

CEA (Carcinoembryonic Antigen): CEA is a protein that is elevated in the blood of some people with colon, rectal, or other cancers. CEA testing is not recommended for general population screening, but it may be used in certain high-risk populations to aid in early detection.

AFP (Alpha-Fetoprotein): AFP is a protein that is elevated in the blood of some people with liver cancer or germ cell tumors. AFP testing may be used in the early detection of these cancers.

CA19-9 (Cancer Antigen 19-9): CA19-9 is a protein that is elevated in the blood of some people with pancreatic, gallbladder, or bile duct cancers. CA19-9 testing is not recommended for general population screening, but it may be used in certain high-risk populations to aid in early detection.

HE4 (Human Epididymis Protein 4): HE4 is a protein that is elevated in the blood of some women with ovarian cancer. HE4 testing may be used in conjunction with CA-125 testing to aid in early detection.

PSA-2 (Prostate-Specific Antigen Isoform 2): PSA-2 is a specific form of PSA that is elevated in the blood of some men with prostate cancer. PSA-2 testing may be used in conjunction with PSA testing to aid in early detection.

PHI (Prostate Health Index): PHI is a blood test that combines PSA, PSA-2, and free PSA to provide a more accurate assessment of the risk of prostate cancer. PHI testing may be used in conjunction with other tests to aid in early detection.

KRAS (Kirsten Rat Sarcoma Virus Oncogene): KRAS is a gene mutation that is found in some people with colorectal cancer. KRAS testing may be used in conjunction with other tests to aid in early detection.

EGFR (Epidermal Growth Factor Receptor): EGFR is a protein that is elevated in some people with lung cancer. EGFR testing may be used in conjunction with other tests to aid in early detection and guide treatment decisions.

In conclusion, biomarkers are important tools for early disease detection. While not all biomarkers are appropriate for general population screening, they can be used in certain high-risk populations to aid in early detection. By knowing about these 10 biomarkers, you can be more informed about the tests that may be used to detect diseases early.

#Biomarkers #EarlyDetection #DiseaseScreening #CancerDetection #ProstateCancer #OvarianCancer #ColonCancer #LungCancer #LiverCancer #PancreaticCancer

References:

1. National Cancer Institute. Biomarkers and Surrogate Endpoints.

2. American Cancer Society. Cancer Screening Guidelines By Age.?

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