Time to "D" -up?
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Time to "D" -up?

Peng Wang Peng Wang

Peng Wang

Procurement B2B Consultant | Physician | C-Suite Medical | Employee Medical Direct

发布日期: 2025年2月28日
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We hear a lot about vitamin D (vitD) levels nowadays, whether you believe it is important or not, it doesn't hurt to get to a therapeutic level, most Americans have low vitamin D. Humans are designed to have this hormone in balance, and it's one of the widely acting dynamic hormones that affects all systems. Chronic low levels can lead to many undesirable effects, so it's "better to believe it than not".

Symptoms related to chronic low-D levels

  • fatigue
  • depressive mood
  • General aches and pains
  • reduced mentation (cognitive function)
  • frequent fractures and thin bones on X-rays

Symptomless (asymptomatic) long-term risks of low vitamin D

  • heart disease
  • metabolic (diabetes)
  • Immune deficiency (infections)
  • Immune irregularities (allergies, rheumatism, cancer)

https://www.scientificamerican.com/article/vitamin-d-deficiency-united-states/

https://pubmed.ncbi.nlm.nih.gov/26204630/

Working professionals, particularly C-suite executives, are working indoors. The amount of UV (ultraviolet radiation) needed to convert the inactive vitamin D in your skin is often insufficient.

The process of natural vitamin D processing takes ~6 months

**UV + skin --> vitD3 --> liver + hydroxylation (OH) --> 25(OH)D+ kidney (OH) --> 1,25(OH)D ---> active vitamin D3

领英推荐

Thanks to Rebecca Oliver for this explanation

https://www.youtube.com/watch?v=Nxvk1G2u2NA

Get there faster by supplementing vitamin D and skip the natural process

  • 15000 units (3x 5000 units capsules) of vitamin D3 weekly --> my preference
  • 1000-2000 units vitamin D3 daily
  • dietary intake of foods with D
  • Get UV when you can*

Vitamin D is fat-soluble (lipophilic), so take it with food.

https://pmc.ncbi.nlm.nih.gov/articles/PMC8074587/table/metabolites-11-00255-t001/

*A friend running a software company travels around the world to scale his business, spoke of an ingenious idea; rather than put up with jet-lag, he takes his laptop work outdoors during sunlight hours instead of napping. A good night's sleep ensues, and he gets "D" -up.

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