Through vaccination, the world of this syringe... Rome era "piston" appeared, the United States MIT "needle free" development

- "capacity minimizes" corona vaccine shortage LDS syringe noted

1853 years standing in a modern form of invention,

neuralgia such a big part in the treatment of diseases

the 1950 years of disposable syringes development

multidose use due to the risk of infection by reducing

the corona virus pharmaceutical supply disruptions

clamoring countries 'vaccination squeeze'

Korea Enterprises develops LDS syringe

“An additional 20 % increase in vaccine production effect”

Countries around the world are thirsting for a novel coronavirus infection (Corona 19 ) vaccine. Vaccines, which are the only means of preventing global disasters, have been developed, but due to insufficient production, countries around the world are eager to secure vaccines by mobilizing their national power. Eventually, the world is fluctuating as vaccine-producing pharmaceutical companies such as Pfizer and AstraZeneca have said that it is difficult to provide the amount of vaccine they planned to supply to 27 European countries within the first quarter of this year. Europe is rebelling against supply, which has decreased by 60 % from its original promise, and is proclaiming a tough response, including legal means. Corona largest in the world, 19 of the patients from the US Food and Drug ( FDA) Finally reached the point of approving the so-called'vaccine squeezing', which increased from 5 doses per vaccine bottle to 6 doses.

In an urgent need for a vaccine, a syringe that can increase the amount of inoculation by 20 % compared to the previous one has been developed in Korea and is drawing attention from around the world. The main character is the'Punglim LDS Syringe' , which a small and medium-sized company called Poonglim Pharmatech, a syringe manufacturer , released on the 19th . As a breakthrough development that can increase the amount of inoculation from 5 doses per bottle to 6 doses with a single syringe is being made, public interest in syringes is emerging. ◇ What kind of syringe is Poonglim LDS syringe? = This syringe developed by Poonglim Pharmatech is a syringe that can significantly reduce the amount of remaining injections and minimize the amount of vaccine discarded. When a general syringe is injected once, the remaining amount of about 84 microliters (μl) or more is left on the tip of the needle or the injection part . This is called the minimum scanning residual amount ( LDS·Low Dead Space ). This amount is just thrown away with the syringe. But Poonglim LDS

Since there is almost no space for the remaining injection volume, the minimum injection amount is only 4μl, which is less than 5% of the general syringe. The amount of chemicals thrown away can be reduced. Therefore, with this syringe, the injection volume of one bottle of Pfizer vaccine can be increased from 5 to 6 or more doses.

The Ministry of SMEs and Startups announced that using the Poonglim LDS syringe has the effect of increasing the production of the Corona 19 vaccine by an additional 20 %. With the amount of vaccine that can get 100,000 people, 120,000 people can get it. This is good news in a situation where the vaccine supply is so difficult that the US approves the squeeze.

Poonglim Pharmatech has passed the LDS performance test of a US pharmaceutical company and has applied for domestic technology patents and design patents related to safety guards. International patent applications such as the United States and the European Union ( EU ) are also being pursued. It has submitted a request for approval for emergency use of syringes to the FDA on the 18th , and is expected to be approved by the end of this month. In particular, Poonglim Pharmatech's injector development process was greatly aided by Samsung Electronics. Samsung Electronics was a car that was distributing a win-win smart factory with the Mid-term Ministry. Through negotiations with vaccine-producing pharmaceutical companies, they discovered that they needed a syringe with no leftovers. On December 24 last year , Samsung Electronics held a countermeasure meeting with Poonglim Pharmatech, a syringe manufacturer. Thirty experts and factories of suppliers in Gumi and Gwangju were put in and started making molds. The prototype came out in just 4 days. Samsung Electronics has improved syringe injection productivity up to 5 times by utilizing ultra-precision mold and injection technology. He even helped in the manufacture of automatic syringe assembly equipment. May 400 of Poonglim Pharmatech production was only ten thousand is 2.5 times the increase in August 1000

It has increased to more than ten thousand. In this process, the mid-term and mid-term ministry also allowed the'fast track of quarantine goods' procedure so that smart factories could be quickly supported, and supported loans at low interest rates through a loan program exclusively for smart factories. This is a valuable achievement achieved through cooperation between the public and private sectors.

◇The history of the syringe, The history of the syringe goes back to the times of ancient Rome. At the time, there is a record that the drug was already injected into the patient with a piston-type syringe. Prior to the 17th century, urethral syringes made of pewter (alloy of lead and tin), bone, and silver were commonly used, and until the mid- 17th century, attempts were made to administer drugs by intravenous injections using animal skins. .

The modern type of syringe was invented in 1853 by Charles Gabriel Prabatz, a French surgeon working in Lyon, France. This syringe is made in the form of a hollow needle combined with an injector (body, piston) that can control the dosage. The needle used here was developed earlier in 1844 by Francis Lind, an Irish physician. This is the first subcutaneous syringe. This syringe allows the drug to be administered by penetrating into the skin without pre-incision in the skin before drug administration.

When Pravatz invented the syringe, Scottish physician Alexander Wood used a glass syringe to visually determine the dose of morphine in the course of treating patients with neuralgia disorders. Wood added a scale to the syringe to measure the dose more accurately.

Since then, syringes of various shapes and materials have been developed. In 1946 , a glass syringe with the same size as the syringe body (outer cylinder) and the pusher (piston) excluding needles was developed. The same standard allows mass disinfection at once without matching each syringe. At that time, if a syringe with incomplete disinfection was used, a mass infection could occur, so glass syringes that could withstand high temperature and high pressure disinfection were mainly used. In order to solve the inconvenience of such multi-use syringes, a plastic disposable syringe was developed in 1950 , and this type of syringe is now widely used.

◇Side effects such as drug misuse = Syringes help drug ingredients to be absorbed into the body quickly and exert their effects, but the disadvantage is that if used incorrectly, there is no proper way to reverse them. If the drug is applied or attached to the skin, it can be washed or removed after checking for misuse.If ingested directly, some can be removed through vomiting, gastric lavage, and enema. I suffer as it is. Intravenous injections can cause the drug to reach the heart in a short period of time, and in the event of a medication accident, can lead to death in an instant.

It is also dangerous to use syringes contaminated with pathogens. It can be transformed into a germ injector in no time. Since general disposable syringes are distributed in a sterile state through a gamma-ray disinfection process, etc., there is no problem, but when used for crimes such as drugs, the syringe is often reused, which can cause serious problems. There are also quite a few people who have pain caused by injections, that is,'injection phobia'. There is also a survey by the National Medical Center ( NHS ) in the UK that 1 in 10 people suffer from rosacea . If the phobia of injections is severe, the person loses strength when receiving the injection and may faint. ◇Evolving syringes to'patch-type syringes' = As such, it is a medical device that is indispensable for human immunity and treatment, but its side effects are also insignificant, so syringe innovation is getting faster. In particular, as efforts to eliminate injection phobia continue, various types of syringes are being developed one after another, including a'patch-type syringe' attached to the skin. Professor Ian Hunter's team at Massachusetts Institute of Technology ( MIT ) in the U.S. developed the so-called'jet syringe' in 2017 . It is a syringe equipped with a system that injects injection liquid at ultra-high speed instead of a metal needle. 200m per second water stream that is thinner than the thickness of a human hair

It releases at a speed, so you can't feel pain. This is an opportunity to be freed from the phobia of injections, which is an irreparable disadvantage of syringes. There was also news that Korean companies and universities have cooperated to develop patch-type vaccines that can prevent diseases without pain in syringes. An official in the medical device manufacturing industry said, "The syringe is a representative invention that has freed mankind from the suffering of disease, and further advanced products will continue to come out with the addition of advanced science and technology in the future."