Targeting Specific Proteins with IVB Technology and Expertise
In this newsletter, we provide two customer stories which exemplify why InVivo Biosystems gene editing services are extremely beneficial compared to off-the-shelf injection mixes. We also share some of the expertise on how we target specific proteins in our projects below!
Customer Stories:
How IVB custom injection mix services have accelerated discovery and research grant application processes.
With injection mixes recently becoming readily available "off-the-shelf" at various organizations, researchers now face a selection and decision-making process that did not exist prior. Researchers now have to decide whether or not there is a need to utilize a custom injection mix service at a Contract Research Organization (CRO) such as InVivo Biosystems rather than ordering a handful of off-the-shelf injection mixes and hoping one works for the project at hand.
At first, ordering made-to-stock injection mixes can seem like a more affordable option. However, the cost of troubleshooting is exceedingly higher. The InVivo Biosystems team has assisted many institutions and organizations with custom injection mix services after teams waste their valuable resources by trying to utilize injection mixes ordered online from other organizations.
In the two customer stories below, we exemplify some of the results given when electing to utilize our team as a resource on a wide breadth of genetic research projects.
Accelerating the grant application process with InVivo Biosystems validated injection mix services.
Dr. Anita Quintana at the University of Texas at El Paso was able to expedite her research grant and approval process thanks to the injection mixes provided by the IVB team.
"Time was really important to me in order to get to a point where we had the [injection] mixes and that they were validated." - Dr. Anita Quintana
See the full story to learn more about how our validated injection mixes enabled Dr. Quintana to specifically target HFC1 proteins:
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Targeting specific proteins and genes with InVivo Biosystems validated injection mix services.
Dr. David Pruyne and Dr. Jeff Amack have also utilized IVB custom injection mix services in projects requiring specific point mutations for narrowing down the specific deletions which cause hypertrophic cardiomyopathy.
"I really enjoyed help and feedback on how to improve the design and what the possibilities were (...) [IVB] did a really good job bouncing ideas back and forth to the point where I ordered a couple of projects and then was pleased enough that I ordered a couple more." - Dr. Jeffrey Amack
See the full store to learn more about how our validated injection mixes enabled Dr. Pruyne and Dr. Amack to disrupt fhod3a and fhod3b genes in zebrafish:
Featured Expertise: Targeted Protein Degradation
Targeted protein degradation is a widespread technique for researchers in understanding the role of a protein at different points of development. Having an understanding of a protein's role during development is the foundation for developing other new tools and discoveries, such as:
In this blog, we talk about the two paramount systems used for inducing protein degradation, the GFP-Nanobody and Auxin-Inducible Degron systems, which our team at InVivo Biosystems has expertise in and has included target protein degradation as a part of multiple customer projects.
We want to hear from you!
Contact our team of industry experts to learn more about how we can assist you in your next upcoming project today.