Supercharge Your VO2max: Top Supplements for Peak Performance

Supercharge Your VO2max: Top Supplements for Peak Performance


Dear Reader,

In this issue of PNOē Insights, we’re diving into the world of supplementation to boost VO2 Max. Understanding the right supplements can make a significant difference in how your body utilizes oxygen during exercise, leading to enhanced endurance and performance. Whether you’re aiming to optimize training or support recovery, these evidence-backed options can help you reach your goals.



VO2 Max is one of the most critical indicators of cardiovascular fitness, measuring the body’s ability to utilize oxygen during intense exercise. A higher VO2 Max translates to better endurance and athletic performance, whether you’re a seasoned athlete or someone looking to improve overall health. Certain supplements, such as beetroot juice, iron, and omega-3 fatty acids, have been shown to play a role in boosting VO2 Max by enhancing oxygen transport and reducing inflammation.

However, not all supplements work the same for every individual, making it essential to tailor the approach based on each person’s metabolic needs and goals.


PNOē’s Perspective on Personalized Supplementation

At PNOē, we recognize that personalized nutrition and training are key to unlocking an individual's true potential. Our breath analysis technology provides precise insights into VO2 Max and overall metabolic health, allowing us to tailor supplement recommendations for each client. By identifying specific deficiencies and understanding how an individual’s body responds to exercise, we can suggest supplements that directly support their physiological needs, whether they aim to increase endurance, enhance recovery, or optimize overall performance.


Actionable Strategies for Boosting VO2 Max

To help you get started, here are some practical, evidence-based strategies to enhance VO2 Max through targeted supplementation:

  • Integrate Nitrate-Rich Foods: Incorporate beetroot juice or other nitrate-rich vegetables like spinach into your diet. Aim for 500 ml of beetroot juice daily before workouts to maximize its oxygen-enhancing effects.
  • Monitor and Supplement Iron Levels: Have your iron levels checked regularly, especially if you experience fatigue during workouts. If needed, consider iron supplements after consulting with a healthcare professional to ensure optimal oxygen transport.
  • Add Omega-3s for Cardiovascular Support: Include 1-2 grams of omega-3 supplements (such as fish oil) daily to reduce inflammation and support better heart function, aiding in improved oxygen efficiency.
  • Combine Supplements with Proper Training: Pair your supplementation with a structured aerobic training program, as regular high-intensity sessions are crucial for maximizing the benefits of these supplements on VO2 Max.

By following these personalized recommendations and leveraging PNOē’s insights, you can ensure that every supplement you take works effectively to enhance your fitness and performance.



How Supplements Boosted VO2 Max for PNOē Clients

At PNOē, we’ve seen firsthand how a personalized approach to supplementation can transform performance outcomes. Here are a few examples from members of our community who have elevated their VO2 Max and overall endurance with targeted supplement strategies:

  • Sarah’s Marathon Success: Sarah, an endurance runner, struggled with maintaining her stamina during long-distance runs. After using PNOē’s breath analysis, she identified low iron levels that were impacting her oxygen transport. With the right iron supplementation plan, Sarah saw a 10% improvement in her VO2 Max within just three months, allowing her to hit a new personal best in her next marathon.
  • David’s Recovery Transformation: A competitive cyclist, David found that muscle soreness and slow recovery were holding him back from consistent training. Through PNOē’s tailored recommendations, he added omega-3 supplements to his routine, reducing inflammation and improving heart efficiency. Within weeks, David experienced faster recovery times and a noticeable boost in his VO2 Max, enabling him to train harder without the usual fatigue.
  • Laura’s Nitrate Boost: Laura, a triathlete, incorporated beetroot juice into her pre-race regimen as recommended by PNOē. The result? A 15% increase in time-to-exhaustion during high-intensity training sessions, helping her power through the toughest segments of her events. Laura credits her enhanced endurance to the combination of PNOē’s insights and the targeted use of nitrate-rich supplements.


The PNOē x BrainTap, Inc Synergy – A Breakthrough in Metabolic and Neurological Optimization

The collaboration between PNOē and BrainTap has unveiled powerful insights into how breath analysis can enhance metabolic and neurological health. In their recent study, integrating BrainTap sessions with PNOē’s breath-based assessments led participants to shift fuel use toward fat, demonstrating improved metabolic flexibility and efficiency. PNOē’s advanced technology captures 23 biomarkers, including VO2 max, fat burn efficiency, and heart rate variability, enabling a personalized, science-backed look into each individual’s metabolic and respiratory performance. Through a simple 8-minute test before and after BrainTap, PNOē reveals crucial metrics like fat versus carb utilization, ideal training intensities, and fuel usage patterns to support optimal health.

By pairing BrainTap’s stress-reducing effects with PNOē’s clinical-grade assessments, this synergy provides a unique pathway for holistic wellness. The combination enhances parasympathetic activity, reduces stress markers, and improves fat utilization, making it ideal for those aiming to optimize both brain function and metabolic health. With VO2 max as a central metric, PNOē establishes itself as the “gold standard” for assessing longevity and biological age, offering measurable insights that help individuals and practitioners drive real, lasting health improvements. This partnership is a leap forward in personalized wellness, providing actionable insights that support long-term health and performance tailored to each individual’s unique profile.


Transforming Research in Men’s Health with Breath Analysis

In an exciting collaboration, nuBioAge , a key PNOē affiliate, teamed up with nuHx and Marius Pharmaceuticals to study the effects of GLP-1 therapies on muscle mass and energy levels in men. The study explores whether testosterone therapy (KYZATREX?) can mitigate muscle loss during weight loss treatment, with results expected in May 2025.

Study Aim

While GLP-1 therapies are effective for weight loss, they often cause muscle mass reduction and energy decline. This study seeks to determine whether combining GLP-1 with testosterone can maintain muscle mass and boost energy levels.

NuBioAge’s Role

As a lead collaborator, NuBioAge designed and oversaw the study, contributing its expertise in longevity medicine. Their work focuses on developing innovative treatments that enhance men’s health and muscle retention during GLP-1 therapy.

PNOē’s Role

PNOē’s breath analysis technology was chosen for its portability, ease of use, and non-invasive nature. It provided real-time, accurate measurements of VO2 Max and metabolic health, allowing the research team to track key biomarkers effortlessly throughout the study.

Why PNOē Stood Out:

  • Portable & Quick: PNOē allowed for testing in multiple locations, offering flexibility.
  • Non-Invasive & Accurate: The device’s precise measurements provided reliable metabolic data in just 8 minutes.
  • Comprehensive Insights: PNOē’s analysis of VO2 Max and metabolism gave the study critical health markers needed for evaluating treatment success.

PNOē’s ability to deliver critical data quickly and reliably made it a cornerstone of this important study, and it continues to demonstrate its value in clinical and research settings worldwide.



Staying hydrated isn't just about physical performance—it’s also key to keeping your mind sharp. A recent meta-analysis sheds light on how dehydration can impair cognitive abilities, emphasizing the importance of maintaining optimal hydration, especially during intense exercise or endurance activities.

Actionable Strategies for Optimal Cognitive Function:

  • Stay Hydrated During Training: Aim to drink fluids consistently before, during, and after exercise, especially during longer sessions.
  • Monitor Hydration Levels: Use tools like weight tracking before and after exercise to ensure hydration remains within optimal levels (≤2% BML).
  • Incorporate Electrolytes: Include electrolyte-rich drinks during extended physical activity to maintain better fluid balance and cognitive function.

<READ THE FULL ARTICLE HERE>



Breaking News: Our Certification Program has been revolutionized! Kickstart your journey with our complimentary course, "Intro to Breath Analysis."

Equip yourself with cutting-edge knowledge and skills to harness the power of breath analysis for optimal health and performance.


Missed our recent webinar with Almir Maljevic ??

In this engaging session, Panos Papadiamantis, co-founder of PNOē, and Almir Maljevic, co-founder of Pro-Fit Health. Strength and Conditioning (PFHSC) in Sarajevo, Bosnia-Herzegovina, discussed how PNOē’s advanced breath analysis technology has transformed Almir’s training and rehab facility into a longevity-focused clinic, helping clients optimize their health and performance.


Here’s what we covered:

  • PNOē and holistic health: Almir shared how he uses PNOē to assess not just musculoskeletal issues, but also metabolic, respiratory, and cardiovascular systems, offering a truly holistic program.
  • Client transformations: From improving respiratory fitness to addressing complex health issues like metabolic inefficiencies, PNOē has expanded Almir’s client base and helped them achieve long-term health results.
  • Support and results: With PNOē's expert support, Almir's clinic offers personalized care plans that lead to faster recovery, improved fitness, and lasting engagement from clients.

If you're looking to enhance your practice or personal wellness journey, this is a must-watch!

<WATCH HERE>


Catch Up on our Previous Webinars

Ready to dive deeper? Explore our full playlist of webinars on YouTube , where we unpack game-changing insights on breath analysis and cutting-edge techniques to take your practice to the next level!

<WATCH HERE>


Join Us at Leading Expos & Conferences This November!

We’re thrilled to invite you to meet the PNOē team in person at these exciting events this November! Visit our booth to experience a free metabolic test and receive a personalized health report on your key metabolic and fitness metrics.

Here’s where you can find us:

Don’t miss this opportunity to experience PNOē’s cutting-edge metabolic testing firsthand and discover how it can unlock insights into your health, optimize your training, and help you live better.

We look forward to seeing you there!


Expanding Our Services

We are excited to announce that you can now access our advanced software without the need for the PNOē device. This means you can take advantage of our powerful apps, PNOē Monitor for health professionals and PNOē Precision for consumers, without the need to purchase the PNOē unit.?

<BOOK HERE>

Whether you're a health professional looking for a comprehensive platform to monitor your clients or an individual aiming to optimize your health journey, our software solutions are now more accessible than ever. Here’s a recap of the features these apps offer:

  • Integrated Client Monitoring: Effortlessly manage your clients’ health with a comprehensive overview that consolidates data from wearable devices, lifestyle logs, and more.
  • In-depth Nutrition and Activity Tracking: Keep track of your clients’ nutrition and activity patterns, allowing you to precisely tailor recommendations and adjustments.
  • Holistic Client Profiles: Understand your clients’ wellness journey in detail, including demographics, lifestyle, and health preferences, to design bespoke programs that align with their unique goals and challenges.
  • Labwork Insights: The lab work view collates data from diverse biometric tests, laying the groundwork for personalized health strategies that are backed by science.


Stay tuned for the PNOē Monitor app.



  • Home Dashboard: A dynamic snapshot of your daily activities, nutrition, and recovery stats, enhanced with science-based advice.
  • Cutting-edge Nutrition Planning: Revolutionize your meal planning with smart alternatives, extensive recipes, and a handy grocery cart builder.
  • Tailored Training & Treatments: Customize your training and treatment plans, track your recovery in detail, and enjoy a personalized experience.


Download PNOē Precision for iOS | Download PNOē Precision for Android


These apps are designed to seamlessly integrate into your daily routine, providing you with personalized insights and recommendations to optimize your health and performance. Stay connected and make the most of these tools to support your wellness journey.



Join the PNOē Community

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Embark on Your Performance Journey with PNOē

Are you ready to explore the depths of your metabolic health? Contact PNOē to schedule your comprehensive metabolic analysis and begin the journey to optimizing your health and performance goals.

Book Your Analysis


Stay Connected

Reach out for inquiries and schedule your demo with PNOē.

Start your journey to holistic wellness today!


Warm regards,

The PNOē Team

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