Study strengthens evidence for HBOT’s role in combating aging
Recent study indicates that hyperbaric oxygen therapy protocol can significantly enhance physical performance and cardiac function.
A new study published in Geriatrics by the Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center, in collaboration with Tel Aviv University, has provided compelling evidence that hyperbaric oxygen therapy (HBOT) can enhance physical performance in aging adults. This randomized controlled trial evaluated 63 sedentary adults aged 65 and older, comparing the effects of a specific HBOT protocol with a control group over three months. The findings demonstrated notable improvements in various physical and cardiac parameters, suggesting a potential intervention to counteract age-related physical decline.
My take on this: HBOT is a medical treatment in which patients breathe 100% oxygen at increased atmospheric pressures. This treatment is known to elevate oxygen levels in the blood and tissues, which can have therapeutic effects. The unique protocol employed in this study, referred to as the hyperoxic-hypoxic paradox, involves intermittent exposure to high oxygen levels, which is hypothesized to induce regenerative effects. Previous studies have shown that HBOT can extend telomeres and reduce immunosenescence, thereby contributing to increased lifespan and healthspan. This study further explores these benefits by focusing on physical performance and cardiac function.
The study involved a rigorous regimen of 60 HBOT sessions over 12 weeks. Participants received treatment daily, with each session lasting 90 minutes at 2 absolute atmospheres (ATA) of pressure. Oxygen was administered in cycles, with five-minute air breaks every 20 minutes. The primary endpoints measured were maximal oxygen consumption (VO2Max) and VO2Max per kilogram of body weight, with secondary endpoints including cardiac perfusion, assessed via advanced cardiac MRI techniques.
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The results were impressive. Participants who underwent hyperbaric oxygen therapy (HBOT) saw notable improvements in their VO2Max, increasing by an average of 1.91 ml/kg/min, with a significant effect size (0.455, p = 0.0034). VO2Max measures how efficiently the body uses oxygen during intense exercise, reflecting better endurance and fitness. Additionally, oxygen consumption at the first ventilatory threshold, where breathing becomes more challenging, also improved significantly, showing a strong effect size of 0.617 (p < 0.001).
Learn more about the HBOT study with insights from Dr Amir Hadanny, Chief Medical Officer at Aviv Scientific and principal investigator at the Sagol Center right HERE .
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3 个月While hyperbaric oxygen therapy (HBOT) is claimed to boost physical performance and cardiac function, it has potential downsides. These include risks like oxygen toxicity, barotrauma, and free radical damage. Overuse might disrupt the body's natural oxygen balance and even suppress the immune system. There's also a lack of long-term data (note: "combating aging"), raising concerns about unknown effects. Additionally, ethical issues around fairness and access, high costs, and the potential for psychological dependence make HBOT's widespread use questionable.
Medical Doctor. Former Elite athlete. Founder Wellgevity.com. Human Flourishing advocate. Longevity BioHarmony. Integrative and Systems Medicine, Emotional Health Expert. Dedicated to empowering others. Always curious.
3 个月Charlie Cox ??♀?
Medical Doctor. Former Elite athlete. Founder Wellgevity.com. Human Flourishing advocate. Longevity BioHarmony. Integrative and Systems Medicine, Emotional Health Expert. Dedicated to empowering others. Always curious.
3 个月When i first started using HBOT back in 2018 i noticed by HRV on oura ring during a "moment" i/e a rest being 25% higher than if i was laying on a bed listening to the same binaural NSDR track. It is in principle enhacing regenerative processes in your body - like plugging your tesla in for a recharge. Yes please. I wish someone would hurry up and create a sleep pod with appropriate hyper/hypo baric settings so we can get more effective sleep and in that accelerate repair processes which essentially become less efficient as we age. ??
Internal Medicine Physician chez Groupe hospitalier CHIREC
3 个月Tomaso Antonacci