Stricter Quality Control in Pharma Shifts the Balance From Spiral to Opposed Jet Mills

Dear Reader,

In our latest white paper titled "Stricter Quality Control in Pharma Shifts the Balance from Spiral to Opposed Jet Mills," we examine an important evolution in the pharmaceutical manufacturing landscape. Spiral jet mills have long been favored for their simplicity and ease of maintenance, and they continue to be a valuable technology for micronization. However, our study, co-authored by Mattie Wiedemeier from Schedio and Stefano Console from Oriento SA, introduces opposed jet mills as a compelling alternative, especially useful in contexts where reducing variability in particle size and material synthesis is critical.

Opposed jet mills utilize gas pressure and the rotational speed of an internal classifier to finely control particle size. This capability ensures consistent milling quality, which is crucial for meeting the stringent quality controls in pharmaceutical production. The study demonstrates that opposed jet mills can maintain uniform particle size distribution without the need for adjustments to pre-validated process parameters, thus offering enhanced process stability and regulatory compliance.

We encourage you to explore how integrating opposed jet mills could complement existing technologies and improve your production processes.

To discover more about this alternative and its benefits, please read the full white paper.

Best regards,

The Schedio Team