Stress Vomiting

I've had stress vomiting and stress headaches for about 16 years now. I have some experience that may help others. I'm going with chemical advice here. Counseling and meditation/mindfulness, exercise, outdoor activities, and sleep also exist. But (unemployment) Financial and housing insecurity is a HUGE causative factor. Middle-class income will upgrade you to middle-class medical benefits, and physicians will not try to keep phone consults to under 3 minutes.

Here are a few ways that real ginger ale can help soothe an upset stomach:

• Ginger contains gingerol, an anti-inflammatory compound that can help relieve nausea and vomiting. The Gingerol helps relax the intestinal tract, reducing gut spasms, pain, and bloating.
• Ginger ale made from real ginger root contains antioxidants like shogaols and zingerones. These compounds are known to help reduce nausea and vomiting.
• The carbonation and ginger provide a soothing effect on the gastric lining and can help relieve dyspepsia. The ginger helps stimulate digestion.
• Drinking ginger ale increases hydration, which can ease symptoms like diarrhea, constipation, and abdominal cramps associated with gastrointestinal distress.
• Ginger has an antiemetic effect and can help reduce motion sickness, morning sickness, and the side effects of chemotherapy.
• Ginger ale made with real ginger has a low caffeine content, making it a nice alternative to sodas when you have a stomachache.
• Combining ginger's anti-inflammatory properties and the liquid's hydrating effects can help settle many minor stomach complaints.

So, in summary, real ginger ale can be an effective home remedy for stomach distress due to its natural gingerol content, hydrating quality, carbonation, and low caffeine level. Just a few sips can help calm many stomach issues.

Extremely high stomach acidity:

Does capsule omeprazole need to reach the small intestine to work effectively?

BL

Yes, omeprazole capsules do need to reach the small intestine intact to be effectively absorbed and provide acid suppression. Here are some key points about why omeprazole needs to get past the stomach:

• Omeprazole is acid-labile, meaning it is degraded by acid. The drug needs to pass through the stomach's acidic environment into the higher pH of the small intestine to remain stable.
• The capsule shell protects the omeprazole inside from stomach acid. Without the capsule, the drug would break down in the stomach before absorption.
• Omeprazole is absorbed primarily in the duodenum of the small intestine. The capsule must dissolve and release the drug here for optimal absorption into the bloodstream.
• The mechanism of action of omeprazole relies on it being absorbed and transported to parietal cells in the stomach. Parietal cells secrete acid - omeprazole blocks the acid production of these cells, but only after absorption.
• Taking omeprazole with food can interfere with proper absorption in the small intestine. Food can delay the capsule from reaching the optimal absorption window.

So, in summary, omeprazole is specially formulated in capsules to withstand stomach acid. It must pass through the stomach and dissolve in the small intestine to be absorbed effectively, providing maximum acid suppression. Without reaching the small intestine intact, omeprazole won't have its desired pharmacological effects.

Will extremely high stomach acidity cause omeprazole capsules to dissolve too early to be effective?

BL

Yes, extremely high stomach acidity can cause omeprazole capsules to dissolve too early, before they reach the small intestine, reducing their effectiveness. Here is a more detailed explanation:

• Omeprazole capsules have an enteric coating designed to withstand stomach acid and dissolve only when the pH rises as it reaches the small intestine.
• But in extremely high stomach acidity (very low pH), the acidity is so strong it can dissolve this enteric coating prematurely.
• This leads to the capsule breaking down and the omeprazole inside being released in the stomach rather than the small intestine.
• Once released, the omeprazole is exposed to the stomach's high acidity, which can degrade and inactivate the drug before it is absorbed.
• Omeprazole must survive transit through the stomach to be absorbed in the small intestine. Premature dissolution prevents the intended absorption.
• Without proper absorption, the omeprazole will not be able to take effect and provide acid suppression as intended.

So, in summary, the extremely low pH of the stomach acid can overwhelm the enteric coating of omeprazole capsules, leading to early dissolution and reduced efficacy. This issue can be addressed by considering alternative formulations or acid reduction strategies. The key is ensuring the omeprazole remains protected from gastric acid to promote optimal absorption.

I had to take Prilosec tablets for the omeprazole to reach my small intestine. Prilosec, for me, is phenomenally, unbelievably awesome.

If your physician says capsule omeprazole is the same as Prilosec (tablet), they are wrong if you have extra potent stomach acid. i.e., when you vomit, you have to rinse your throat and mouth immediately to stop a painful burn to your skin.

Prilosec prescriptions are unavailable to VA patients and others on low-income medical plans. Fight to get a generic tablet form or get Prilosec added to fight intense stomach acid.