Sept. 14 - 20, 2024
NEW STUDY—Effectiveness of modified vaccinia Ankara-Bavarian Nordic vaccine against mpox infection: emulation of a target trial
This study aimed to assess the real-world effectiveness of the MVA-BN vaccine against mpox infection using a target trial emulation approach in Ontario, Canada, involving 9803 men with certain health histories. The results showed that among 3204 vaccinated men, there were significantly fewer mpox infections compared to 3204 matched unvaccinated controls, leading to an estimated vaccine effectiveness of 58%. These findings suggest that one dose of the MVA-BN vaccine is moderately effective in preventing mpox infection during an outbreak.
NEW STUDY—Adverse outcomes and mortality in individuals with eating disorder-related electrolyte abnormalities in Ontario, Canada: a population-based cohort study
This study investigated the link between electrolyte abnormalities and health outcomes, including mortality, in individuals with eating disorders using a retrospective cohort analysis in Ontario. Among 6163 patients, those with electrolyte abnormalities had significantly higher mortality rates (15.7% vs. 5.6%) and were more likely to experience hospitalizations and various health issues, such as acute kidney injury and fractures. The findings emphasize the need for careful monitoring of electrolyte levels in this population and suggest refining the definitions of eating disorder severity while advocating for further research in different regions.
领英推荐
NEW STUDY—Days at home after traumatic brain injury: moving beyond mortality to evaluate patient-centered outcomes using population health data
This multicenter retrospective cohort study aimed to validate "days at home" (DAH) as a patient-centered outcome measure for assessing morbidity following moderate to severe traumatic brain injury (TBI) using Ontario's linked health administrative data. Analyzing data from 6,340 patients, the study found a median DAH of 70 days at 180 days post-injury, with significant associations between lower DAH and factors like older age, higher health resource utilization, and greater injury severity. The study concludes that DAH180 days is a valid and responsive measure for evaluating outcomes in TBI patients, highlighting its potential for use in future population-level assessments.
Lunch & Learn Series: National Centre for Truth and Reconciliation – University of Manitoba?
September 23 – 27, 2024??
Lunch and Learn sessions are aimed at an adult audience, and open to the public, and will be hosted virtually over Zoom Webinar and streamed to YouTube.? For a full list of lunch and learn sessions, click here.?
Video Recording: Canadian Medical Association Apology to Indigenous Peoples
The Canadian Medical Association (CMA) made the apology Wednesday at a ceremony in Victoria, attended by representatives of First Nations, Metis and Inuit peoples. To view the recording, click here.