SECRETed Hot News #1
SECRETed Project H2020
Sustainable Exploitation of bio-based Compounds Revealed and Engineered from naTural sources
The SECRETed concept
The amphiphilic nature of biosurfactants and siderophores provide enable the exchange of their chemical parts?towards the development?of new-to-nature compounds.
Scientific articles
Methods, protocols, and results. The SECRETed consortium published 8 scientific articles over the last 6 months. See the publications…
SideroTec HiSen? assay
The test detects siderophores and iron chelation molecules at levels as low as 5nM; that is 100 times more sensitive than any other assay.
Systems biology
A database with 255 Biosynthetic Gene Clusters that encode the biosynthesis of 176 siderophores and 185 biosurfactants.
Biosurfactants production
More than 100 thermophilic strains screened; optimized cultivation conditions for increased biosurfactants yields; development of isolation and purification methods from the cell-free culture broth.
Heterologous production of rhamnolipids
A top-20 strains passed the evaluation for further genome sequencing and identification of biosynthetic gene clusters. Saccharide esters from marine strains; optimized production and purification; antiviral and antimicrobial activity; microbial chassis and protocols for heterologous production.
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