SciProtech's Innovative Product - SARS-CoV-2 Antigen Detection Antibody Pair (Colloidal Gold Method)

Antigen Screening, Nucleic Acid Diagnosis

1. Nucleic acid detection is the most accurate and sensitive way, and it is the basis for the diagnosis of new coronavirus infection;
2. Self-check at home, easy to use;
3. Fast to test out results about in 10 minutes;
4. The reagents can be well preserved at room temperature for 15 months.

SARS-CoV-2 Structure and Immunodetection Antigens

The new coronavirus (SARS-CoV-2) has four main structural proteins: spike protein (Spike protein, S protein), nucleocapsid protein (Nucleocapsid, N protein), membrane protein (Membrane protein, M protein), package Membrane protein (Envelope protein, E protein). The S protein is a very important surface protein of the coronavirus and is closely related to the infectivity of the virus. The S protein contains S1, S2 and a receptor binding domain (RBD, which binds to the new coronavirus receptor ACE2). The N protein is abundant in coronaviruses with few mutations, and is a highly immunogenic protein involved in genome replication and regulation of cell signaling pathways. S protein and N protein can be used as antigens for new crown immune detection.

The Principle of Colloidal Gold Detection of New Crown Antigen:

1. After the sample is dropped on the sample well, if there is a new crown N antigen in the sample, it will be recognized by the gold-labeled antibody on the binding pad to form an antigen-antibody complex, which continues to flow towards the absorbent pad.
2. There is another antibody against the antigen on the test line. The antigenic epitope recognized by this antibody is different from that of the gold-labeled antibody, so the same antigen is recognized by both antibodies at the same time, and the gold-labeled antibody is intercepted at the test line. part of the color.
3. The amount of gold-labeled antibody in the mobile phase is surplus, and it will continue to flow in the direction of the absorbent pad. The quality control line is a secondary antibody specifically for gold-labeled antibody. The quality control line has a very strong ability to retain gold-labeled antibody, forming a quality control String. If the quality control line does not develop color, the test result is invalid.

Introduction of SciProtech:

The antibody discovery team of SciProtech Co., Ltd. originated from the Chinese Academy of Sciences. It has continuously undertaken the task of antibody engineering under the national "863" plan for 25 years. It is the pioneer and founder of the field of genetic engineering antibodies in China.

SciProtech has a complete full-species antibody discovery technology system, covering the key links of target preparation, antibody screening, antibody optimization and antibody evaluation. Integrate hybridoma, phage antibody library and single B cell technology to provide comprehensive and detailed solutions for the needs of different species of antibody screening and optimization.

SciProtech has three core technologies:

(1) Pharmaceutical-grade electrofusion hybridoma technology;

(2) Rapid construction of tens of billions of large antibody library technology;

(3) High-throughput/full-species antibody molecule conversion technology.

SciProtech provides high-quality antibody discovery technology services for domestic and foreign antibody drug companies, cell therapy companies, in vitro diagnostic companies and scientific research institutes. In the future, we will continue to uphold scientific concepts, empower the global antibody industry, create a "practical" antibody discovery technology platform with ingenuity, and develop "really useful" antibody products for customers.

Genfine Biotech (Beijing) Co., Ltd. is a national high-tech biotechnology enterprise integrating R&D, production, sales and technical services. As the main investment body of SciProtech, it will build SciProtech into a world-class antibody discovery technology service provider and protein reagent supplier through the integration of all aspects of resources.