Science, Hacks, and Magic: Drug Discovery Explained
Biotech Primer
Expert-Led Life Sciences Training and Certifications for Non-Scientists to Advance Your Career
by Biotech Primer
Discovering drugs isn’t a one-size-fits-all process. It’s a mix of strategies, blending creativity, science, technology, and even luck. A drug discovery program aims to produce preclinical candidate molecules that show evidence of biological activity against a disease target. From serendipitous breakthroughs to AI-designed molecules, here’s a rundown on how scientists find medicines that change our lives.
Old-School Discovery
Phenotypic drug discovery (PDD)?is the classic method where scientists test compounds on cells, tissues, or organisms to see what happens. There is no specific target; it is just pure trial and error. It’s like tossing ideas at the wall and waiting for one to stick. This serendipitous strategy led to the discovery of artemisinin, a lifesaving antimalarial drug.
Sniper Method
Target-based drug discovery (TDD)?takes a more focused approach. Here, researchers zero in on a specific biological target, like a rogue protein driving disease, and develop drugs to neutralize it. It’s all about precision, like with the drug pimavanerin (Nuplazid) used to treat Parkinson’s disease psychosis.
Biotech Primer Inc. provides engaging, interactive training courses tailored for non-scientists in the Biotechnology, Pharmaceutical, Molecular Diagnostics, and Medical Device sectors. These courses, developed by industry experts, simplify complex scientific and regulatory concepts for professionals seeking to navigate and contribute effectively to the healthcare sector. With flexible learning options like on-demand online classes and live sessions, Biotech Primer has educated over 150,000 professionals since 2001, making it a go-to resource for understanding the science behind healthcare innovation.