Science brief - July-August 2024

Science brief - July-August 2024

ESRF - The European Synchrotron ESRF - The European Synchrotron

ESRF - The European Synchrotron

The ESRF is an international research lab, where X-rays are used to unlock the secrets of matter.

发布日期: 2024年8月29日
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New, enzyme-embedded plastic degrades fast

Scientists have developed a biosourced plastic embedded with an enzyme that ensures rapid biodegradation and compostability, overcoming the hurdles of currently used plastics. They used the ESRF to solve the structure of the enzyme.

Journal: Nature

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Transmitted by mosquito bites, filarial worm pathogens can reach the lymphatic nodes where they cause severe chronic pain and swelling of tissues. Credits: Hoffmann, G. et al,

Novel therapeutic approach for neglected tropical diseases

Elephantiasis and river blindness are two neglected tropical diseases affecting 120 million people worldwide and caused by parasitic worms. The bacteria Wolbachia is essential for the survival of these worms.

Now scientists at Université Grenoble Alpes and INSERM have found a novel therapeutic approach developing boron-based compounds targeting Wolbachia and disrupting the microbiota of the worms.

For this project, which started 15 years ago, the researchers have used the ESRF structural biology beamlines extensively.

Journal: Science Advances

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Elsa Panciroli, from the National Museums Scotland and corresponding author of the publication, examines the samples of the kursatodon kirtlingtonesis fossil. Credits: Duncan Mc Glynn.

Mammals grew more slowly in the Jurassic than today

Analysis of two unique Jurassic fossil discoveries from the Isle of Skye (Scotland) have shown that mammals in the time of the dinosaurs grew more slowly and lived longer than mammals today. Synchrotron studies of the fossils at the ESRF contributed to the research.

Journal: Nature

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A new form of uranium identified at the ESRF

Scientists from Helmholtz-Zentrum-Dresden-Rossendorf and the Rossendorf Beamline at the ESRF have detected for the first time the U(III) form of uranium, shedding light on the fundamental chemistry of uranium systems.

Journal: Nature Communications

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3D cinematic renderings of the control and diseased heart in anatomic orientation. Epicardial fat has been removed digitally to show course of the major coronary arteries plus detail of smaller arteries penetrating into the myocardium which are not typically seen on clinical CT. In the control (A), the coronary arteries remain close to the epicardial surface while in the diseased heart (B) they are lifted away by epicardial fat increasing the perfusion distance between the major coronaries and the myocardium. Segmentations and high resolution detail of coronaries in the diseased heart are also shown in Figure 5. Credit: Brunet et al., Radiology.

A unique atlas of the human heart

Scientists led by the University College London (UCL) and the European Synchrotron (ESRF), have, for the first time, imaged two whole human adult hearts, one healthy and one diseased, down to the cellular level in 3D, using an innovative X-ray technique called Hierarchical Phase-Contrast Tomography (HiP-CT). This new atlas of the heart can potentially lead to medical applications.

Journal: Radiology

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