"Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions"

"Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions"

"We show that somatic (copy number variant) CNVs may contribute a small but significant part of the genetic architecture of (schizophrenia) SCZ, mirroring previous findings of rare germline and de novo CNVs,1,23 but involving a much more modest proportion of cases. The estimated excess burden of sCNV in SCZ would be 0.4%, which represents a preliminary estimate..."?


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