With ROI, Time is Money…Sometimes

With ROI, Time is Money…Sometimes

I’ve developed a number of ROI models for companies seeking ways to demonstrate how their technology product will pay for itself 2, 5, 10 times over based on the cost savings, incremental revenue, etc. expected from using their product.

Nearly every time I’ve developed one of these models for clinical research software products, I’ve been asked or questioned about including some version of the opportunity cost of lost prescription drug sales from delays in trials. And why not? The numbers get large and juicy very quickly- a recent estimate suggests $500k per day! Use my product, reduce your clinical trials by 2 months, and you’ll generate an extra $30m in future sales!

I always say no, because drug development is a low probability business. ~10-15% of drugs that enter Phase I ultimately get approved (years into the future), ~30-35% that enter Phase II get approved, and perhaps ~60% that enter Phase III get approved (source ).

Dollar based ROI estimated must be tangible, probable, and reasonably within the customer or product’s control to realize. Future prescription sales certainly feels tangible, but only in the unlikely event the drug under development is approved, and that approval is not within the customer’s control (and definitely not within the product’s control).

Telling the customer your product is worth buying because they MIGHT achieve more sales years in the future IF a regulator they don’t control approves that product comes off as desperate, disingenuous, and just plain salesy. In my first ROI modeling project, I spoke to ~10 people in my client’s customer segment, and snuck in this concept to gauge whether there was any appetite for believing this type of ROI. Every response was strongly negative, and I quickly pivoted away.

So How Can You Quantify ROI for Time Savings?

Time savings still matter and can generate tremendous ROI. Here are a few ways I look at time savings and in an ROI framework:

  • Customers who outsource parts of their operations often incur significant duration-based “carrying costs” with those vendors, and those costs often scale with time. In clinical research, these carrying costs are enormous, tangible, and 100% probable (believe me, I used to be the one sending the change orders).
  • Customers may employ numerous internal contractors, consultants, and even employee roles who tenure is tied to completing projects or achieving milestones. Completing projects and achieving milestones faster means the organization can flex down those costs sooner than planned.
  • Projects often involve require software products, and software is commonly paid for on a duration basis (especially in clinical research). If your product helps a customer finish projects more quickly, they will spend less on technology costs.
  • If your product reduces the time (hours) to complete tasks, you can quantify that savings, especially if there are hourly-based people involved.

Each item above is quantifiable in an ROI model. You can't achieve exact precision- and the customer wouldn't believe you if you somehow did- but through internal and external benchmarks, and simply asking your customers, you can find reasonably ranged estimates that will help customers think about how using your product will benefit them financially over time.

I emphasize ranged estimates because 1) you won’t achieve perfect precision with these estimates, and 2) you don’t want to find yourself negotiating an ROI estimate. Using a high/low set of ranges creates a collaborative discussion with the customer, where they feel free to say “I actually think your 2-3 months should be 1-3”, or “that 40%-50% reduction is probably 30%-40%”. Instead of pushing back, you can simply say “ok” and adjust the ranges. The result is not a binary “$1,356,238” in theoretical ROI but “$1.2-$1.8m” with appropriate supporting assumptions that you and your client counterpart can use to further discuss your product across their organization.

Bottom Line

Use time wisely in ROI modeling. Keep it tangible, probable, and reasonably estimated. Be creative and persistent in exploring all materials sources of ROI from saving time. Avoid theoretical future benefits based on approvals or milestones that are outside their control and well-known to be significantly less than 100% guaranteed. Don’t give the appearance of exact precision when it doesn’t exist. Enjoy the process and let me know your own best practices.


I specialize in pricing strategies for service and technology providers. Contact me to discuss solutions for your organization.

Sandy Robbins

Finance and Commercial Leader with a Passion for Defining, Quantifying and Delivering Value in the Clinical Trials Space.

4 个月

Great post! I agree it’s best to stick with relative ROI components such as % reduction in time or errors. A good pharmaceutical product manager should be able to translate that efficiency into savings that is relaxant for a particular product. Where I struggle is convincing people of the ROI associated with reducing change orders and delays. We know that most trials delay snd incur other scope changes that result in additional cost. But how many pharma companies actually plan for this in their budgets and forecasts?

Joe O'Rourke

Head, Commercial Development, Walgreens Clinical Trials

4 个月

As someone who in the past was involved in these types of fantastical ROI calculations ("Spend $3 million with us and accelerate your study 3 months, achieving $300 million in future NPV sales opportunity!").....agreed wholeheartedly. ROI should be about present-tense options. Line up your customers options earnestly and evaluate the pros and cons of each with them....and if you aren't the clearest cut ROI/business case, call it out. Trust and integrity wins more than hard to believe ROI calculations, because at the end of the day people buy from teams and organizations they can trust to deliver upon their needs and give them a better future state.

Michael Bassick

Product Management Leader | Process Excellence | Healthcare Technology | Clinical Operations | Agile Development | Product Evangelist | Customer Value Advocate

4 个月

Great article, Joel. Thanks for pushing back on the future sales opportunity cost myth.

Jeff Smith

Experienced CEO | Strategic Advisor & Consultant | Board Member | C-Suite Partner

4 个月

excellent post Joel White. Ken Getz recently wrote about daily trial costs across phases in Applied Clinical Trials Magazine. Time based savings are a much more relevant and quantifiable approach as you have so nicely laid out!

Elias Sayias, B.Sc. CCRA

Founder of ILIKOS CG | Fractional Executive | Business & Corporate Development Consultant | Expert commercial strategist for contract research organizations (CROs)

4 个月

Great perspective Joel White. From a commercial standpoint we need to understand Sponsor development strategies much better along with the impact of market dynamics...

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