RESEARCH NEWS: Menopause prevention using ovarian tissue freezing, reducing biological age with chemical reprogramming, microplastics linked to cancer

This week we see research starting to be able to reprogram cells, towards improving cellular function and ultimately age reversal. Pretty great! Ultimately it would seem we are getting better at tinkering with cells and processes precisely, and I am super excited (and scared) to see where genetic and cellular tailoring takes us over the next few years and decades.

More evidence that microplastics are problematic, this time in cancer ??

Might be time to have a look at how much plastic we’re wrapping our bodies in, and change back to natural fibre clothing.

Pretty exciting -and not something I’d seen previously- extending reproductive lifespan and delaying menopausal onset by re-implanting self ovarian tissue. Wow!?

Menopause is something that is finally getting some of the attention it deserves and yet needs more. Further options for managing it are wonderful to see.

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Jabe Brown , Founder (Melbourne Functional Medicine)

Preventing menopause indefinitely through ovarian tissue freezing

Ovarian tissue freezing could delay or prevent menopause indefinitely by preserving fertility and hormonal function. This involves freezing and re-implanting ovarian tissue, extending reproductive lifespan and mitigating menopause-related ageing effects.

Achieving cellular rejuvenation and longevity with partial chemical reprogramming

Partial chemical reprogramming in mouse fibroblasts using a compound cocktail can reduce biological age. Multi-omics analysis shows significant improvements in mitochondrial function, gene expression, and a reduction in ageing-related metabolites, indicating potential for in vivo age reversal.

How GLTD impacts ageing and age-related diseases like Alzheimer’s

Gene-length-dependent transcription decline (GLTD) in ageing organisms results in longer genes showing decreased expression. This decline, linked to DNA damage and polymerase stalling, contributes to ageing and age-related diseases like Alzheimer’s. Targeting GLTD offers potential therapeutic avenues for enhancing healthspan and longevity.

Long-term health risks of polystyrene microplastics in colorectal cancer cells

Polystyrene microplastics are taken up by colorectal cancer cells, increasing cell migration and potentially promoting metastasis. These particles persist in cells, accumulate in non-proliferating tumour areas, and transfer during cell division, highlighting their potential role in cancer progression and long-term health risks.

To read these articles in full, visit our research feed.

#longevity #ageing #aging #lifespan #healthspan #brainhealth #cancer #epigenetics # microplastics #cognitivefunction #cognitive performance #genetics #memory #mitochondrialhealth #menopause #reproductivehealth #biologicalage #womenshealth