Promega Preview (UK) - May 2023
Promega UK
We're the UK Promega life sciences team, sharing technical tips, our event info, science news, articles and blog posts.
Welcome to the next issue of our monthly Promega Preview newsletter on LinkedIn, designed especially for our UK followers.
New Product: Anti-HiBiT Monoclonal Antibody
HiBiT-tagged proteins are typically measured using the bioluminescent signal generated by adding Nano-Glo??HiBiT detection reagents, providing for precise measurement of changing protein levels over 7 logs of linear dynamic range. The new Anti-HiBiT Monoclonal Antibody expands detection options, enabling applications such as immunoblotting, immunofluorescence, immunoprecipitation and fluorescence-activated cell sorting (FACS). Its high affinity and low background binding allows detection of many HiBiT-tagged proteins at endogenous expression levels.
Detect Cholesterol from a Variety of Biological Samples
The Cholesterol/Cholesterol Ester-Glo? Assay is a rapid and sensitive bioluminescent method for detecting cholesterol from a variety of sample types, including lysed cells, tissues, medium and serum samples. No organic extraction, extreme heat or centrifugation is required and the assay has linear cholesterol detection up to 80μM.
New Product: Automated Total Nucleic Acid Extraction for In Vitro Diagnostic Pathogen Testing
The Maxwell??CSC Pathogen Total Nucleic Acid Kit, used with the Maxwell??CSC Instruments, is designed for automated, benchtop extraction and purification of total nucleic acid from a broad range of sample types. The preprogrammed method on the Maxwell??CSC Instruments enables extraction of total nucleic acid from different sample types simultaneously in a single extraction run, maximising laboratory time and efficiency.
Watch Video: Illuminating the Brain with a New Bioluminescence Imaging Substrate
Bioluminescence imaging is a powerful tool for non-invasive studies of the effect of treatments on cells and tissues. Su et al., in a recent publication in Nature Chemical Biology, reported the results of evaluating and optimising NanoLuc??substrates in brain bioluminescent imaging. These efforts led to the development of cephalofurimazine (CFz) and some exciting results.
New Webpage: PARP and DDR Pathway Drug Discovery
Promega offers a variety of assays and technologies to facilitate PARP/DDR pathway drug discovery. These include target engagement assays that evaluate the binding of compounds to the pathway components, activity assays for PARP and kinase, as well as assays to monitor cell health.
Events
Save the Date for Biologics Symposium
Join the Promega team and fellow research scientists for our 7th Biologics Symposium Thursday, 9 November 2023.
Webinars
Do you want to use fewer plates, tips and cells in time-course experiments? Join our webinar to learn about real-time, live-cell kinetic assays that allow you to collect multiple time points with a single plate setup, ensuring you never miss a critical time point.
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