Professional Sample Preparation Before Sequencing Overall Solution

Application Insight

Sample preparation before sequencing often requires processes such as nucleic acid extraction, concentration determination, fragmentation, library preparation, and library quality control. The whole process is time-consuming and requires high professionalism. Any errors in any process may result in errors in the final sequencing results. The process of library preparation has become an important factor affecting experimental efficiency due to its complex steps and high requirements for experimental operations.

The automated NGS library preparation workstation can achieve standardized operation of the library preparation process, and relies on high-precision pipettors and high-performance functional blocks to effectively improve the accuracy and reproducibility of experiments, greatly reducing the difficulty and cost of library preparation before sequencing.

The organic integration of Allsheng automated extraction, library preparation platform, and quality control equipment can achieve the whole process automation of sample preparation.?Auto-NGS series library preparation platform can cover different sample throughput and functional requirements, and has high downstream adaptability. The innovative functions integrated and added are in line with practical applications, bringing new assistance to automated library preparation.

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Professional Category Advantages Create Leading Solutions

Allsheng sample preparation before sequencing overall solution covers the whole process from sample nucleic acid extraction, sample quality control, library preparation to library quality control. All instruments are independently developed and produced by Allsheng, and each process is compatible with multiple types and models of products. Users can freely choose according to the sample type and quantity.

Leap-Pure S24 nucleic acid purification system has a maximum reaction system of up to 15 mL and supports automated extraction of FFPE blocks without the need for external dewaxing and lysis. Feyond-F100 fluorescence microplate reader can detect concentration of 96 samples in one run. Auto-NGS 100R has obtained Class II medical device certification (registration certificate number: Zhejiang Medical Device Approval No. 20242221518), which can achieve basic library preparation; other models of machines include fluorescence detection blocks, which can realize sample-to-library. GeneCE-100 bio-fragment analyzer has a minimum resolution of 1 bp, and there are relatively few similar instruments in China.

Flexible and Open Library Preparation Platform

Allsheng Auto-NGS series automated NGS library preparation workstation currently includes 4 models: Auto-NGS 100R, Auto-NGS 100RF, Auto-NGS 180S, and Auto-NGS 200, which can cover the whole process automation library preparation requirements for samples from 1 to 96.

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1-96 Samples, Low, Medium, And High Throughput Full Coverage

Auto-NGS 100R: A basic automated NGS library preparation workstation with an 8-channel pipettor design that meets the basic library preparation needs of 1-24 samples. It is suitable for research laboratories, clinics, laboratories conducting pathogen detection research, etc.

Auto-NGS 100RF: An advanced automated NGS library preparation workstation with an 8-channel pipettor design and built-in fluorometer block, meeting the needs of the whole process library preparation for 1-24 samples. It is also suitable for research laboratories, clinics, laboratories conducting pathogen detection research, etc.

Auto-NGS 180S: A specialized automated NGS library preparation workstation with a 24-channel pipettor design that allows for flexible pipetting of 1-24 channels. Equipped with a built-in fluorometer block, it meets the whole process library preparation requirements for 1-48 samples and can collaborate with grippers and plate stacking for continuous operation. It is suitable for assembly line projects, testing centers, etc.

Auto-NGS 200: An advanced automated NGS library preparation workstation with a 24-channel pipettor, which can achieve flexible pipetting of 1-24 channels. It has a built-in fluorometer block and can meets the whole process library preparation requirements for 1-96 samples. It is suitable for disease control, customs, testing centers, etc.

Comprehensive Block Configuration, No Intervention in the Whole Process

Auto-NGS series automated NGS library preparation workstation is equipped with functional blocks such as PCR, temperature control, mixing, magnet, fluorometer, etc., according to different throughput and plate layout design. The addition of the fluorometer block makes it possible to automate the whole process and has lower costs compared to external microplate readers.

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Open Software Design, Intuitive and Easy

Auto-NGS series software adopts a graphical interface design, which allows for quick and easy mastery of software usage without the need for programming basics. It's with multiple built-in preset parameters that can obtain the best parameters without repeated experiments.

Open software design that can suitable for the application needs of various library preparation kits in the market

X-Channel Pipettor Design, High-Precision Pipetting

Self-developed multi-channel pipettor meets the high-precision pipetting requirements of 1-200 μL and supports free selection of 1-24 channels, without the need to gather samples before running.