Precision Meets Simplicity | EasyAna dsRNA Quantitative Detection Kit (DD3509EN): Methodologically validated and Reliable product
Vazyme Biotech
A Global Supplier Dedicated to Design, Manufacture and Application of Bioactive Proteins.
Accurate dsRNA Detection for mRNA Early-Stage Research, Process Development, and Quality Control. The effect of dsRNA on the effectiveness and safety of mRNA drugs has been introduced before >> https://bit.ly/3uSiUBA.?
With the development of the industry, the impurity residue standard of mRNA preparation is also increasingly perfect. In April 23, the draft USP added ELISA method to detect dsRNA, realizing the quantitative detection of dsRNA.?Vazyme Biotech announces the launch of dsRNA quantitative detection Kit (ELISA)?with rigorous methodological validation，precisely measure dsRNA levels in both natural and modified IVT mRNA products.
EasyAna dsRNA (Modified) Quantitative Detection Kit (ELISA) 2.0 is developed based on a double-antibody sandwich ELISA platform to quantitatively detect the amount of dsRNA in the IVT product or synthesized mRNA solution.
How We Achieved Excellence
--- Time-Saving: Slash over 20 hours* of laborious ecoating time.
--- Error Reduction: Minimize the risk of inaccuracies caused by human handling.
*Compare with workflow using Antibody & Standards
--- Enable Antibodies Compatible with Different dsRNA Sequences
Bid farewell to the hassles of extensive sequence corrections, reduce the R&D and validation efforts.
Methodology has undergone rigorous validation in accordance with the ICH Guideline M10 on Bioanalytical Method Validation,including precision and accuracy,selectivity,specificity etc. 10 indicators.
Core data presentation
At 1 mg/ml and 2 mg/ml, this kit detects dsRNA exclusively, without reacting to dsDNA, ssDNA, or different-length/sequence ssRNA. Additionally, at 10 μg/ml, various IVT reaction enzymes don't interfere with the detection.
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