SR-Tiget is looking for curious, motivated and talented individuals to join its laboratories through the International PhD Course in Molecular Medicine at the Vita-Salute University.
For all the information about the application process and more details on the PhD program and the individual projects, please read here.
Find below an overview of the projects available in SR-Tiget laboratories:
Gene and Cell Therapy Curriculum:
- Engineering thymic selection to control the development of alloreactive T Cells to promote acceptance of allogeneic transplantation (Supervisor:
Andrea Annoni
- Lab webpage)
- Targeting the hematopoietic stem cell niche to improve gene therapy for hemoglobinopathies (Supervisor:
Annamaria Aprile
- Lab webpage)
- Dissecting hepatocyte heterogeneity in liver growth to improve in vivo gene therapy (Supervisor:
Alessio Cantore
- Lab webpage)
- Cell-free DNA as an early molecular response biomarker of CAR-T cell activity and efficacy (Supervisor:
Daniela Cesana
- Lab webpage)
- Gene expression dynamics of blood cell emegence (Supervisor:
Andrea Ditadi
- Lab webpage)
- Epigenetic regulators of inflammatory responses (Supervisor: Renato Ostuni - Lab webpage)
- Preclinical development of hematopoietic stem cell gene therapy for Morquio syndrome (Supervisor:
Stefania Crippa
- Lab webpage)
- Targeted delivery of orthogonal cytokines to safely improve CAR-T function within the tumor microenvironment of solid tumors (Supervisor:
Nadia Coltella
- Lab webpage)
- Studying the interplay between senescent cancer cells and the immune micronvironment in acute myeloid leukemia (Supervisor:
Raffaella Di Micco
- Lab webpage)
- Addressing the Unknowns of VEXAS syndrome by Single-cell Multiomic Clonal Tracking and Targeted Genome Editing (Supervisor:
Samuele Ferrari
- Lab webpage)
- Mobilization and Antibody-Mediated Conditioning: A Dual Approach to Maximize Chemotherapy-free Hematopoietic Stem Cell Therapy (Supervisor:
Attya OMER
- Lab webpage)
- In vivo genetic engineering of liver metastases to modulate immune circuits (Supervisor:
Mario Leonardo Squadrito
- Lab webpage)
Basic and Applied Immunology Curriculum:
