PCos, Hirsutism, acne and Irregular periods

Today we brought a serious issue - P Cos,? hirsutism, acne and irregular periods

Polycystic Ovary Syndrome (P C O S) - is a hormonal disorder causing enlarged ovaries with small cysts on the outer edges.

P COS can cause missed or irregular menstrual periods, excess hair growth, acne, infertility, and weight gain.

Polycystic ovary syndrome (P COS) is a common hormonal condition that affects women of reproductive age. It usually starts during adolescence, but symptoms may fluctuate over time.

Polycystic ovary syndrome can cause hormonal imbalances, irregular periods, excess androgen levels and cysts in the ovaries. Irregular periods, usually with a lack of ovulation, can make it difficult to become pregnant. PCOS is a leading cause of infertility.

People with Polycystic ovary syndrome are more likely to have other health conditions including, type 2 diabetes, hypertension (high blood pressure), high cholesterol, heart disease and endometrial cancer (cancer of the inner lining of the uterus). reference World Health organization website.

Symptoms of Polycystic ovary syndrome? can be reduced through lifestyle changes. Eating a healthy diet and getting enough exercise and Birth control medicines (contraceptive pill) can help regulate the menstrual cycle and reduce symptoms. Along specified medicines can reduce acne or unwanted hair growth caused by PCOS.

Although hirsutism and acne can be considered cosmetic in nature, they cause significant social embarrassment and emotional distress. This are unwanted male-pattern hair growth on a woman's face, chest and back.

In addition Acne a skin condition that occurs when hair follicles plug with oil and dead skin cells. Acne is most common in teenagers and young adults. Symptoms range from uninflamed blackheads to pus-filled pimples or large, red and tender bumps.

Cyproterone + Ethinyl Estradiol is a combination of two hormonal medicines: Cyproterone and Ethinyl Estradiol which treats Polycystic ovary syndrome symptoms, Cyproterone acetate, being both an antiandrogen and a progestogen, must be administered in women together with an oral estrogen in a “raven & sequential regime” to ensure cyclic withdrawal bleedings and to preclude conception.

?The combination of the anti-androgen cyproterone acetate (2 mg) and ethinyl estradiol (35 mg) (co-cypridiol) is of proven efficacy in management of symptoms of both hyperandrogenism and menstrual abnormalities.

?Cyproterone acetate combined with estradiol results in a subjective improvement in hirsutism compared to placebo.

?An effect of the estrogenic-progestogen combination upon the adrenal androgen synthesis has been established, It has a dual effect upon hyperandrogenism in hirsute patients. It decreases the 5a reduced androgens which are believed to arise principally in target tissues, while it also decreases the androgens secreted by the ovaries as well as the adrenals.

Cyproterone acetate lowers levels of testosterone in the body and also blocks testosterone from reaching the cancer cells. This means it can slow or stop the growth of prostate cancer.

?Cyproterone acetate is metabolized by the enzyme, forming the active metabolite 15beta-hydroxycyproterone acetate, which retains its antiandrogen activity, and reduce progestational activity.

?Cyproterone acetate is stored in adipose tissue which causes a marked depot effect when high doses are used. It has now been an accepted treatment of hirsutism for almost two decades with a reported good clinical response.