Patients who restrict are more likely to have damaging mutations.

In this second infographic, I break down the mutations by how damaging they are predicted to be. Patients with restriction are much more likely than patients without eating disorders to have highly damaging mutations. Interestingly, patients who primarily struggle with binge eating are in between the other two groups. Several of the patients in the 'binge eating' group have a remote history of restriction as teenagers and then transition into mostly binge eating as adults.