Patient Case Study: Colon Cancer with Lymph Node and Liver Metastases

Patient Case Study: Colon Cancer with Lymph Node and Liver Metastases

Are you heading to RSNA this December? We’re thrilled to join the radiology community for this landmark event! As we prepare for the conference, we’re sharing a series of patient case studies that highlight the life-changing potential of proactive healthcare and advanced whole-body MRI (WB-MRI).

Our latest case features a 72-year-old male who opted for a WB-MRI screening as part of a renewed commitment to his health before embarking on a six-month work trip abroad.?The scan revealed multiple liver metastases from colorectal adenocarcinoma, with regional lymph node involvement but no disease beyond the liver—a finding linked to a better prognosis and treatment options. The patient was referred for an expedited oncology consultation, enabling timely evaluation and potential life-prolonging interventions, including surgical resection.

Here’s the full story…

Patient History

  • A 72-year-old male, who had previously not participated in standard preventive healthcare and screenings, sought a whole body MRI (WB-MRI) screening as part of a renewed focus on his health.? The scan was scheduled prior to a planned six-month work trip abroad to ensure there were no immediate health concerns that required attention.

Findings

  • His scan showed multiple liver metastases (sites showing spread of cancer) from an adenocarcinoma of the colon (primary/original cancer site) with regional spread to the lymph nodes that drain towards the liver.?
  • No disease was detected beyond the liver, a finding associated with improved prognosis and available treatment potential in metastatic colorectal cancer.

Follow-Up Care

  • The patient was given an expedited oncology consult recommendation for further evaluation and management of disease, which offers a chance at improved survival (based on current best practices) for life-prolonging strategies that include surgical resection (removal of cancerous tissue).?

How the WB-MRI Impacted Patient Care

  • Colorectal cancer (CRC) is the third most common cancer worldwide; approximately 25-50% of these patients develop cancer in the liver. Screening colonoscopy is the gold-standard for earliest possible colon cancer detection, as well as prevention by removal of precancerous polyps. In this case, for a patient who had previously not adhered to standard preventive health screening recommendations, WB-MRI played a pivotal role in this patient's care by uncovering potentially treatable colorectal cancer with liver metastases, at advanced stage but one still potentially amenable to life-prolonging treatment options.
  • Early Detection Beyond Symptoms: Unlike colonoscopy, which focuses solely on detecting cancer within the colon, the opportunistic detection of the still asymptomatic colon cancer by the WB-MRI enabled simultaneous identification of distant metastases and triaging of the next most important steps in clinical management towards a potentially improved prognosis prior to further progression of disease.
  • Prognostic Clarity: By identifying metastatic disease confined to the liver and regional lymph nodes, the scan provided critical prognostic information, emphasizing the potential for successful intervention with specialized advanced care.
  • Improved Treatment Timeline: Pre-symptomatic identification facilitated timely transition to oncologic care, enabling discussions around cutting-edge treatment options.

3D maximum intensity projection (MIP) whole body diffusion weighted magnetic resonance imaging (DWI) image cropped to the torso.?Red circle: primary colon cancer mass. Blue circle: Suspected lymph node metastases. Green circle: Hepatic metastases.
Left image: Axial DWI image at the mid abdomen (green circle colon diffusion restricting hypercellular mass; red circle adjacent focal abnormal diffusion restricting lymph nodes, suspicious for mets). Right image: Axial T2 image at the mid abdomen (green circle: primary colon cancer mass).
Axial T2 image at the upper abdomen. Multiple hepatic soft tissue masses compatible with metastases.

We’re inspired daily by stories like this from our patients and radiology team. Stay tuned—more compelling cases are on the way!

Attending RSNA? Swing by booth #1239 to connect with us. We can’t wait to see you there!


References:

Martin J, Petrillo A, Smyth EC, et al. Colorectal liver metastases: current management and future perspectives. World J Clin Oncol. 2020;11(10):761-808. doi:10.5306/wjco.v11.i10.761.

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