Pathogen reduced platelets
Ontario Regional Blood Coordinating Network
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Dr. Shuoyan Ning Assistant Professor, Division of Hematology & Thromboembolism, Department of Medicine, McMaster University Co-Director of Operations, Hamilton Regional Laboratory Medicine Program Medical Officer, Canadian Blood Services?
Dr. Michelle Zeller Associate Professor, Division of Hematology & Thromboembolism, Department of Medicine, McMaster UniversityCo-Director of Operations, Hamilton Regional Laboratory Medicine ProgramMedical Officer, Canadian Blood Services
Pathogen-reduced platelets are a new platelet component manufactured by Canadian Blood Services. There are two types of pathogen-reduced platelets: pooled platelets psoralen-treated (PPPT) and apheresis platelets psoralen-treated (APPT). PPPT was first introduced in 2022 at select hospitals, and national rollout is currently underway. APPT is pending Health Canada approval.?
Cerus INTERCEPT Pathogen Inactivation Technology (PIT) is used to manufacture pathogen reduced platelets. Pathogen inactivation technology uses amotosalen and UV light to inactivate viruses, bacteria, protozoan parasites, and white cells. ?INTERCEPT has been approved for use in the European Union since 2002 and gained FDA approval in the United States in 2014. Clinical trials and large multinational hemovigilance databases have confirmed the excellent safety profile of this technology.?
Key benefits of pathogen reduced platelets includes .... Read More