Parkinson's Datasets for Researchers

The majority of our clients at Fios Genomics work in drug discovery and development. In the course of our work applying bioinformatics analyses to datasets to further their research, we use data from various publicly available sources.

We have found that research foundations can be a great resource for research datasets as they often have large data repositories focused on a specific condition or disease, such as Parkinson's disease. Also, the data is often made available for free or at low cost to encourage research advances to benefit those with that disease or condition.

Since today is World Parkinson's Day, we wanted to highlight some of the Parkinson's datasets available from the Michael J. Fox Foundation, which champions data sharing for research progress:

Parkinson’s Progression Markers Initiative (PPMI): This ongoing longitudinal study collects clinical, imaging and genetic data as well as biological samples to further biomarker discovery and validation and therapeutic development.

PPMI RNA Sequencing Project: This project gathered transcriptomics data from raw sequencing reads of 1,600 PPMI whole blood samples.

Fox Insight: This online study collects data from patients about their lived experience of Parkinson’s disease.

BioFIND: This observational clinical study aims to identify and verify biomarkers of Parkinson’s disease, using clinical data and biological samples from participants with and without Parkinson’s disease.

LRRK2 Cohort Consortium (LCC): This consortium of three closed studies created a Parkinson’s database and biorepository. These store data and samples from people, with and without Parkinson’s disease, who carry mutations in the LRRK gene.

Levodopa Response Trial Wearable Data: This study assessed the feasibility of using wearable sensor data to measure the severity of Parkinson’s disease symptoms.

Please feel free to share this article with anyone who would find it useful. Also, if you know of any other publicly available Parkinson's disease datasets, please comment to let us all know about them.

Thank you.

-Breige McBride,?Content and Social Media Manager, Fios Genomics