Ode to a MastCell
Credit - Jane Green MBE

Ode to a MastCell

ODE TO A MAST CELL

Cytokine storm rages, histamine release

Multi biological reactions that never cease

Swelling, blisters, itching, redness and pain

Genetically based, the cycle erupts again

Nowhere to go, nothing helps, sleep deprived due to painful welts

A hidden agenda from cells deep within,

For the hypermobile community another battle to have to win https://www.sedsconnective.org/post/when-that-mast-cells-flare-the-storm-gathers-pace

Mast cells, a type of blood cell, play an important role in the body’s immune system. They reside in all body tissues and form part of the body’s initial defence system. Mast cells react to foreign bodies and injury by releasing a variety of potent chemical mediators, such as histamine when activated.

In healthy people, these chemicals will act beneficially to protect and heal the body, In a person with MCAS these same chemicals are inappropriately triggered and when released and have a negative effect on the body.

Amongst the triggers are a variety of different foods, exercise, chemicals, fragrances and stress. Many sufferers struggle to identify their triggers and continue to discover new triggers for many years after diagnosis. EDS Ehlers-Danlos syndromes and hypermobility Spectrum Disorders often have MCAS/MCAD which might be part of a bigger picture like dysautonomia.

J Green MBE webinar 'issues with tissues' October 2020.

Mcas images depicting IBS pain and hives, wheals and rashes on skin



#MCAS #hypermobility #EDS #HSD

Jane Green MBE FCCT

Founder & Chair SEDSConnective | MBE for Neurodivergence Hypermobility 2023 | Autistic ADHD Dyspraxia Lead | Keynote Speaker | Ex-Assist Headteacher | Disabled, Carer I school dropout I FCCT I Autodidact

9 个月

I used to have huge flares and they were exacerbated by everything. It led to anaphylaxis and hospital visits, constant fear of food due to reflux, pain and vomiting but told it was not physical. I still do get flares and had one for over 2 months recently due to mould toxicity , mcas angiodema but I sadly didn't realise it was real until a few weeks into it . I did not seek medical help as I know they do not understand it but did request some medications mainly antihistamines blockers and inhibitors. I then took positive actions to remove the mould (due to a flood) and felt much better. Our make up of understanding our senses and cognitive emotions are also key here as well as connective tissue responses.

Maria Carter BSc MSc

Owner/Publisher at Swan & Horn | Publishing Consultant | Medical Editor | Publishing Services Provider

9 个月

Well put! And well done for raising awareness!

Jennie Meadows

Photographer & Neurodivergent Lived Experience Consultant

9 个月

This was mentioned to me by my diagnosing, appropriately trained private GP who confirmed my Hypermobility Spectrum Disorder (HSD). Mast Cell Activation is onnected to my dermogtaphica (skin writing), which isn't painful for me, but can appear as something more sinister to others. Contemplating, the information, does this explain why many ND individuals experience such a viscarel reaction to criticism or when something is visually breaking a perceived pattern? Or an odd bit of audio when a rhythm is broken or note off-point? <more coffee required> ??

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