Obvious lab advice ??
Hi everyone!
Here's some obvious lab advice.
No explanation needed.
Catch you next time,
?? Lessons learned from 18 months in a cold room
Understandably, one of them was that when it's 4 degrees, even if you're wearing 4 layers underneath your lab coat, focusing on purifying plant enzymes is impossible. But our Chief Scientific Officer's more profound realization was that he could've avoided the whole experience entirely with Synthace.?
??? Talking shop with Life Science Success
From realizations that dads might actually know what they're talking about, to optimistic outlooks on the future, Markus' conversation with Life Science Success' host Don Davis covered a lot of ground. A must-listen for those pondering how to make technology play a leading role in life sciences innovation. ?
?We're taking questions for DOE Office Hours
On August 15th at 4 pm BST / 11 am ET, we're loaning out our DOE evangelists Sid Sadowski and JAJA Arpino's?decades of experience with Design of Experiments. Whether you need help choosing a design or building models during analysis, submit a question in advance and come along to hear their answers.? ??
?? Content we're loving
Why we loved it:
There's a reason so many people travel to Turkey for hair transplants on the cheap—for many, having a full head of hair is a confidence booster.
领英推荐
That's why this study showing that a simple sugar, 2-Deoxy-D-ribose (2dDR), could be potentially harnessed as a topical treatment for hair loss happening in male pattern baldness, is particularly exciting.
2dDR was previously found to stimulate angiogenesis, proliferation of endothelial cells, and accelerate wound healing, so its potential for hair regrowth was explored in comparison to the go-to current treatment Minoxidil, known to cause various side effects. Looking at a mouse model of male androgen-induced hair loss, 2dDR was able to achieve 80-90% hair regrowth seen with Minoxidil, possibly offering a cheaper and safer hair loss treatment alternative.
Why we loved it:
Textbooks might tell you that mitochondria produce reactive oxygen species (ROS), which then cause oxidative DNA damage and mutation. But it turns out this notion has actually never been directly validated until now.
Mitochondria produce ROS in the form superoxide (O???) , which is rapidly converted to the more stable hydrogen peroxide (H?O?), known to oxidize DNA.
This study employed the enzyme D-amino acid oxidase (DAAO) fused to various localization tags to assess location dependent response to H?O?. The findings went against the long-accepted dogma: Physiologically relevant concentrations of H?O? released from mitochondria-bound DAAO did not cause nuclear DNA damage!
Why we loved it:
A perfect example of what can go wrong when you're pressured to get things done to a deadline (and how drama isn’t just for reality TV shows). Even scientific research projects, particularly at an international scale, have their moments, given the huge number of people involved and the high stakes to succeed.
This report delves into archived emails and documents showing some of the controversies surrounding the Human Genome Project, a 13-year global scientific endeavour to deliver the first sequence of the human genome.
Why we loved it:
Lab automation is still somewhat of a new field—and due to lack of widely available educational resources, can be a bit of a mystery to many scientists.
We’re excited to see Madeline Wolf launch this project intended to close this gap. We'll be keeping our eyes peeled for what comes next.
About Synthace
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Field Application Scientist II at Synthace
4 个月Life lessons for the lab and beyond!
Scaling Tech Brands Worldwide | Marketing I Techstars & CEMS grad
4 个月some of this is obvious life advice (gamification, read the room, back up your data! Love it!
Customer Success Manager at Synthace
4 个月I'm definitely guilty of taking pipette tips from the middle of the box... ??