Now, attomole-level detection of low-abundance biomarkers using standard ELISA workflows
Introducing Exazym? — the BOLD immunoassay signal amplifier
All of us at Cavidi are excited to share some good news for life science researchers. We have just released a game-changing innovation in precision health that brings ultra-sensitive detection levels to conventional immunodiagnostic assays. The product’s name is Exazym? and it is available today.
Our goal with Exazym? is to provide best-in-class sensitivity without proprietary equipment or commitment to locked-in systems. That’s why we have designed Exazym? as an add-on immunoassay reagent kit that can be added to any ELISA workflow, using standard laboratory equipment, previously optimized ELISA antibody pairs, and established testing protocols. Exazym? is based on a new detection method called Binding Oligo Ladder Detection, or BOLD for short. This new amplification technique is ideally suited for detecting low-abundance analytes. It offers up to 100x signal amplification gains and 50x lower limit of detection.
Ideal for Detecting Low-Abundance Biomarkers
? Up to 100x signal amplification and 50x lower limit of detection
? Compatible with standard ELISA equipment and protocols
? Minimal extension of assay time
? Retain validated antibody pairs
? Consistent results across multiple runs and samples
? High sensitivity, specificity, repeatability, and accuracy
Ultra-Sensitivity that’s Ultra-Practical
Many potential biomarkers exist at levels below the detection limits of current techniques, posing challenges for research as well as clinical and diagnostic applications across medical specialties. While a number of ultra-sensitive proprietary systems have emerged in recent years, they typically require specialized instrumentation, software, and new protocols. This elevates costs and introduces logistical complexities that hinder adoption on a large scale. Exazym? overcomes these challenges by offering researchers attomole-level detection using standard immunoassay workflows and equipment.
A Plug-and-Play Solution for Rapid Implementation
Simply adding Exazym? to existing immunoassay protocols will provide significantly improved sensitivity without compromising accuracy or specificity. The plug-and-play design makes it quick and easy to get started with Exazym.? Our add-on reagent kits are compatible with previously optimized antibody pairs, standard laboratory equipment, and established testing protocols. Whether you're using common colorimetric, fluorescence, or chemiluminescent immunoassays, Exazym? seamlessly integrates with existing plate readers and analyzers. This ensures rapid implementation ‘‘out of the box,’’ without assay modification, extensive revalidation, or new capital equipment.? Plus, Cavidi’s experienced Support Team is on hand to assist you with any questions, drawing on over 30 years of expertise in biomarker detection.
Try Exazym? and see what you’re missing
Originally published on our website blog.
Senior Consultant, Magtech Sweden AB
10 个月It’s truly?wonderful?to witness the fruits of?countless years of dedication?in the Cavidi lab now being?published. Our achievement in?signal amplification?across various assays and platforms is a?remarkable success! ??????