Novel human anti-VEGFR2 human antibody for cancer therapy
Dr. Ruei-Min Lu
Assistant Research Scientist Antibody R&D core facility in Academia Sinica
We discovered and engineered human antibody targeting VEGFR2 from phage display library. It showed anti-tumor activity for prostate cancer and leukemia. The efficacy and safety of this antibody is as well as ramuciramab, the US FDA-approved anti-VEGFR2 Ab. The data was most recently published in Cancer Science in Oct 2019. https://onlinelibrary.wiley.com/doi/full/10.1111/cas.14208