Niagen: Backed by research, looking to the future

ChromaDex CEO Rob Fried on the importance of NAD+ in cellular health and longevity and the science behind Niagen.

Longevity.Technology recently announced the launch of its consumer products division, expanding its commitment to evidence-based longevity solutions. The division’s first product, FLT LONGEVITY, is formulated with a precise combination of clinically studied ingredients designed to support cellular function and enhance healthspan.

A key component of this formulation is Niagen, ChromaDex ’s proprietary form of nicotinamide riboside (NR), recognized for its ability to increase NAD+ levels. NAD+ plays a critical role in cellular metabolism and repair, making it a fundamental target for interventions aimed at promoting long-term health, and the inclusion of Niagen demonstrates the formulation’s foundation in rigorous scientific research.

My take on this Developed in collaboration with industry-leading suppliers and supported by human trials, FLT LONGEVITY reflects Longevity.Technology’s emphasis on transparency and efficacy. Our partnership with ChromaDex – a company known for its high standards in NAD+ research – reinforces our commitment to delivering scientifically validated, high-quality formulations. We sat down with Rob Fried , ChromaDex CEO, to find out more about why NAD+ is crucial for cellular health, Niagen’s clinical research and future applications and what the future of longevity might look like.

Rob Fried on 'Safety first'

We’ve shown is that the safest and the most efficient way to elevate NAD levels is through nicotinamide riboside. And the only legal, safe, proven, regulatory-approved version of nicotinamide riboside is Niagen, which ChromaDex has studied repeatedly over the years, has patented and received regulatory approvals.

There are companies that are promoting NAD boosters. A lot of people are actually, literally selling NAD, which is the same as sawdust. It actually probably does some harm to take NAD itself. The NAD molecule is a very large molecule and it’s a nucleotide. It’s the same problem that NMN has, which means there’s a phosphate group on the perimeter, and that blocks entry into the cell. So you ingest it, makes its way into the bloodstream, it endeavors to get up into the cell – and fails. That attempt, which is dramatic with NAD, a little less dramatic with NMN, causes friction and inflammation. Eventually the phosphate breaks off and the NAD molecule breaks apart into smaller molecules, one of which is actually NR, which then upregulates up into the cell very cleanly and efficiently and then eventually converts back into NAD once inside the cell. So the safest, most efficient and best way, which is proven over and over again with countless studies, is Niagen.

Get exclusive insights on NR-related research and future plans, straight from Rob Fried. Watch the full video right HERE. Plus, discover how Tenaya Therapeutics ' new funding will accelerate gene therapies for heart disease.

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