New Week - New Awesome Publications

Every week I check Google Scholar to see what publications have come out using our extracellular matrix products (Advanced BioMatrix).

This week there were 3 new ones that really stood out to me, because they each have unique ideas that can possibly be translated into future products and applications.

Publication #1: "Prechondrogenic ATDC5 cell attachment and differentiation on graphene foam"

(Bowman's note - Graphene seems to have endless possibilities, and this is yet another example).

Link: https://pubs.acs.org/doi/abs/10.1021/acsami.9b14670

Product Used: ECM Select Array Kit was used to determine that ATDC5 cells were found to adhere to collagen types I and IV, and fibronectin more extensively than other ECM molecules screened. Researchers then functionalized the graphene with fibronectin to improve cell attachment.

Publication #2: "Cell Migration Designed by Constructive Machine Learning"

(Bowman's note - Machine learning is one of the waves of the future. It's nice seeing it becoming integrated with biotech and research).

Link: https://onlinelibrary.wiley.com/doi/full/10.1002/open.201900222

Product Used: PureCol type I collagen was used to form 3D hydrogels for analyzing cell migration.

Publication #3: "Rapid fabrication of collagen bundles mimicking tumor-associated collagen signatures"

(Bowman's note - anybody studying how cancer travels, and how to slow that down, has the potential to save millions of lives. It is only a matter of time).

Link: https://www.biorxiv.org/content/10.1101/815662v1.full

Product Used: PureCol type I collagen was used to create collagen bundles aligned by a microfluidic device, which elicited cancer cell contact guidance and enhanced their directional migration. The collagen bundles seemed to "provide a highway for cancer cell invasion."

If you're interested in starting a new biotech company, be sure to read my article from last week on the Product Adoption Curve and how it affects start-ups.