A new ligase on the block: AZ R2D Ligase
Bernd Striberny
![Bernd Striberny]()
Bernd Striberny
Research Manager at ArcticZymes Technologies ASA, team leader, project manager and inventor
The R2D Ligase demonstrates remarkable efficiency in catalyzing the formation of a phosphodiester bond between the 5′-end phosphate of RNA and the 3′ hydroxyl group of DNA within nucleic acid duplexes. Its unprecedented versatility allows it to accept both RNA and DNA as substrates and efficiently link them in either direction. This novel capability holds immense potential for driving innovation in molecular biology and biotechnology, opening doors to groundbreaking applications in these fields.
These findings have now been published by Sigurd Eidem Gundes? et al. in the Biotechnology Journal under the following DOI: https://doi.org/10.1002/biot.202300711. Enjoy reading!
Clinical Research Assistant at Vancouver Coastal Health | Honours B.Sc. High Distinction Graduate from the University of Toronto
11 个月Wow, this could have a major impact on RNA-based therapeutics by improving stability and specificity! Looking forward to seeing how this transforms diagnostics and therapeutics in the future.
Life Science Executive | CEO | Strategy | P&L | Leadership | Commercialization
11 个月Well done Bernd and team. Congratulations with getting this paper published!