Natural anti-microbial enzyme Lysozyme

Lysozyme is an antimicrobial enzyme that is found in a wide variety of organisms including birds, mammals, plants, insects, and bacteria. The lysozyme of chicken egg white has been most extensively studied. The enzyme attacks broad-spectrum of bacteria that are Gram-positive and Gram-negative in certain cases with little negative effects. The enzyme even works on some viruses. Therefore, it has been widely used as antimicrobial preservative for food and non-specific immunological factor for feed.?

Lysozyme Features:

1. The pure product of lysozyme is white or slightly white crystalline or amorphous powder, easily soluble in water, insoluble in acetone and ether.

2. The suitable temperature for the action of lysozyme is 35°C~50°C, and the optimum temperature is 37°C; the suitable pH of lysozyme is 5.3~7.4, and the most suitable pH is 6.8. Its aqueous solution is stable at pH 3~11 and is not easily destroyed by gastric acid .

3. Lysozyme will not be inactivated by the treatment of organic solvents. When transferred to an aqueous solution, the activity of lysozyme can be fully restored.

4. Lysozyme has strong thermal stability and is the most heat-resistant enzyme known. At pH 4~8, the enzyme activity remains above 90% when treated at 100°C for 1 minute. At the same time, lysozyme can be frozen or dried, and its activity is stable.

5. Lysozyme has a wide antibacterial spectrum, not only has a prominent effect on G+ bacteria, but also has a good inhibitory effect on some G- bacteria, especially the effect on drug-resistant bacteria is more obvious.

6. Lysozyme is a natural protein, non-toxic, harmless, non-residue, non-drug resistance, high biological safety, and meets the requirements of green, safety, health and environmental protection.

7. The combined use of lysozyme and antibiotics can increase the efficiency by 2 to 10 times, reduce the amount of antibiotics, and effectively control drug residues.

Lysozyme Application in food preservation

In view of the wide distribution and effective antibacterial activity of lysozyme, it has broad application prospects as a safe antibacterial agent in food preservation and preservation, antibiotic substitute products, antibacterial drugs, and medical diagnosis.

In the dairy industry, it is used to prevent the “late swelling” caused by proliferate of Clostridium tyrobutyricum, a contaminating agent present in milk used in cheese production. It can also be used as a preservative for fruits and vegetables, soy products, meat and fish,wine and not- pasteurized beer.

Lysozyme Application in Feed Industry

The negative effects brought about by the abuse of antibiotics are becoming increasingly prominent, and the resistance of bacteria and fungi to antibiotics is gradually increasing. The emergence of these problems has promoted the development and research of new antibiotic substitutes by researchers. Lysozyme has the following aspects in feed applications due to its safety, no residue, and bactericidal effect on pathogenic bacteria:

1.Feed preservatives and fungicides, adding lysozyme to feed can prevent mildew, prolong the storage period of feed, and reduce unnecessary loss.

2.When the piglets are weaned, the secretion of the pancreas suddenly drops, the animal's digestive function appears short-term obstacles, and the nutrient absorption decreases, resulting in diarrhea. Adding lysozyme preparation can effectively control diarrhea caused by indigestion. Because lysozyme can increase the activity of endogenous proteases and promote the production of anti-inflammatory polypeptides, it has the effect of resisting and eliminating inflammation.

1). Relieve diarrhea in piglets, regulate intestinal microecological balance, and improve intestinal health of suckling piglets;

2). Enhance piglet immunity, improve disease resistance, and improve production efficiency;

3). Adjust the health status of sows, reduce postpartum inflammation of sows, and improve the health of newborn piglets;

4). Reduce piglet morbidity and reduce the use of antibiotics.?

3.Promote digestion and absorption, which is beneficial to animal health. Without any antibiotics, adding lysozyme preparations to the feed can promote the digestion and absorption of nutrients in the feed, increase weight gain and feed remuneration, and reduce death. It has been reported in the literature that the chickens fed the same chicken coop with lysozyme feed enzyme preparation, compared with the control group, the number of eggs laid increased by 7.04%, the egg weight increased by 7.06%, the egg production rate increased by 5.76%, and the feed conversion rate increased. 6.69%.

Lysozyme For Poultry:

1). Enhance poultry immunity, improve disease resistance, reduce morbidity and mortality;

2). Improve poultry feed stool and watery stool, improve intestinal health, and regulate intestinal micro-ecological flora;

3). Improve egg poultry oviduct inflammation, reduce digestive tract problems, and improve egg quality.

Yotabio Ingredients is a bio food ingredients & enzymes manufacturer from China. We focus on natural food preservation and enzyme solutions. We offer two types of lysozyme for food and feed application, welcome to contact us for details.