Meet us at Cosmetic-360 in Paris to discover Mechanisms-Based Cosmetic

Meet us at Cosmetic-360 in Paris to discover Mechanisms-Based Cosmetic

Our state of the Art understanding of the skin mechanisms already led to disruptive quick win discoveries to restart innovation in the cosmetic business as we did in medicine.

Skincare: Strong integrated understanding of the global systems: Download our Mechanisms-Based Cosmetic presentation during Cosmetic 360, october 16-17 in Paris (Carrousel du Louvre)

Mechanisms-Based Cosmetics is the cosmetic version of our core business Mechanisms-Based Science

Programs conducted and validated with targets and compounds

  1. The mechanisms associated with constitutive and facultative epidermal pigmentation
  2. The mechanisms associated with senile/solar lentigines (aging issues)
  3. Components specific to pigmentation from production to destruction
  4. Microbiota & Skin Mechanisms

Programs started ready for experimental validation

  1. Skin pigmentation Mechanisms
  2. Skin pigmentation Modulation
  3. Skin aging Mechanisms
  4. Modulation of skin hydration
  5. Modulation of the lipid constituents of the skin barrier
  6. Novel Hair Loss Mechanisms
  7. Skin Contact Allergy Mechanisms

Bio-Modeling Systems is the world’s first Mechanisms-Based Cosmetics company that successfully changed the discovery paradigm, addressing the complexity of life sciences mechanisms and the digital ? garbage in garbage out ? reality through CADI? Discovery.

We offer to R&D Executives, robust alternative decision-making to de-risk, save time, costs, and novel cost-effective diagnostics/therapies for their businesses.

Created in 2004, profitable since 2006, thanks to our recurrent clients, we already confirmed of CADI Discovery in Pharma, Biotech, Cosmetics, Nutrition and digital-Health.

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Contributor to The first reference book on “Computational Biophysics of the Skin” edited by Prof. Bernard Querleux , scientific chairperson of the International Society for Biophysics and Imaging of the Skin. R&I L’Oréal.





We propose to R&D Executives, robust alternative decision-making to de-risk, save time, costs, and novel cost-effective diagnostics/therapies for their businesses.

  1. GO-NO GO decision before product acquisition or for portfolio risk analysis.
  2. GO-NO GO decision before next development phase.
  3. R&D program Rescue for a program facing critical issues during its lifetime.
  4. External R&D “B plan” program when the “A plan” cannot be rescued.
  5. Exploratory Discovery program to discover novel causal mechanisms concepts.
  6. Novel Hypotheses for therapeutic and/or diagnostic solutions discovery.

to support science based cosmetics in

  1. Skin care
  2. Skin Aging
  3. Skin Hydration
  4. Skin Pigmentation
  5. Skin Allergy

We conducted successful programs in skin pigmentation with big cosmetic player. We are now free to work with anyone.

Our state of the Art understanding of the skin mechanisms already led to disruptive quick win discoveries to restart innovation in the cosmetic business as we did in medicine.

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