Med. Chem. Res. 2024, Vol 33, Iss 6

Med. Chem. Res. 2024, Vol 33, Iss 6

Medicinal Chemistry Research | 2024 | ?Volume 33, Issue 6, ?is now available online.

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In this issue

Review Article

Recent pharmacological insights about imidazole hybrids: a comprehensive review

Samet Poyraz, Metin Y?ld?r?m, Mehmet Ersatir

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Review Article

Exploring nucleoside analogs: key targets in the viral life cycle - advancing strategies against SARS-CoV-2

Roopal Garg, Raveen Kumar, Ritika Srivastava, Richa Srivastava

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Original Research Article

Design and synthesis of indole-based elipticine analogues as topoisomerase IIβ inhibitors

Mardia T. El Sayed, Alaadin E. Sarhan, Huriyyah A. Alturaifi, Selwan M. El-Sayed, Ghada S. Hassan, Nehal A. Hamdy, Shahenda M. El-Messery, Mamdouh M. Ali

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Original Research Article

A very promising antibiofilm activity against Candida albicans from an in vitro screening for antimicrobial, antibiofilm and antiproliferative activity of new synthesized 4-cinnamamido- and 2-phenoxyacedamido-1H-pyrazol-5-yl)benzamides

Fabiana Plescia, Valentina Catania, Antonella D’Anneo, Demetrio Raffa, Marianna Lauricella, Domenico Schillaci

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Original Research Article

Synthesis of novel benzothieno-[3,2’-f][1,3] oxazepines and their isomeric 2-oxo-2H-spiro[benzothiophene-3,3’-pyrrolines] via 1,4-dipolar cycloaddition reaction and their evaluation as cytotoxic anticancer leads

Mohammed M. Al-Mahadeen, Areej M. Jaber, Jalal A. Zahra, Mustafa M. El-Abadelah, Walhan Alshaer, Mutasem O. Taha

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Original Research Article

Discovery of HNPC-A188: a novel acaricide containing trifluoroethyl thioether and pyrimidin-4-amine

Ting Xiao, Aiping Liu, Xingping Liu, Fujun Zhong, Guojun Li, Zhichang Huang, Zai Zhang, Yeguo Ren, Jiang-Sheng Li, Weidong Liu

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Original Research Article

Morpholinated curcuminoids against urinary bladder cancer cells: synthesis and anticancer evaluation

Pawel Bakun, Malgorzata Kucinska, Paulina Koby?ka, Joanna Ku?mińska, Tomasz Koczorowski, Dariusz T. Mlynarczyk, Lukasz Popenda, Katarzyna Górska, Ma?gorzata Kasperkowiak, Marek Murias, Anna Jelińska, Tomasz Goslinski

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Original Research Article

Candida albicans ergosterol disorders as a consequence of the new sulfone derivative action mode

Monika Staniszewska, Michalina Kazek, Marta Rogalska, Anna Wojewódzka, ?ukasz Kuryk, Zbigniew Ochal

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Original Research Article

Synthesis and in vitro biological activity of chalcone derivatives as potential antiparasitic agents

Koketso J. Setshedi, Richard M. Beteck, Kayhan Ilbeigi, Dorien Mabille, Guy Caljon, Lesetja J. Legoabe

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Original Research Article

Design and synthesis of benzo[d]imidazo-6,7-dihydrobenzo[d] imidazo[2,1-b]thiazol-8(5H)-ones as potent anti-infective agents

Rakesh K. Bollikanda, Yana L. Esaulkova, Abburi Naga Pranathi, Devendra Nagineni, Nagaraju Chirra, Anna A. Muryleva, Pedapati Ravikumar, Vladimir V. Zarubaev, Srinivas Kantevari

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Original Research Article

Design and synthesis of novel factor XIa Inhibitors with bicyclic isoquinoline and naphthalene fragments

Yi Zhang, Linjun Dai, Yi Tan, Yongpeng Yu, Junhao Xing, Feng Yang, Boquan Ren, Yan-Jun Xu, Qing Li

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Original Research Article

Synthesis and antiviral property of polysulfate-grafted maleimide-based enediynes

Zhuoyu Li, Zhe Ding, Haonan Cheng, Xiaofan Zhang, Houjun Zhang, Gary Wong, Yun Ding, Jiaming Lan, Aiguo Hu

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