Med. Chem. Res. 2024, Vol 33, Iss 2

Medicinal Chemistry Research | 2024 | ?Volume 33, Issue 2, ?is now available online.

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In this issue

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Review Article

Bioactivities and the structural modification of Parthenolide: a review

Jie Wu, Xiaoqian Wang, Yunlei Hou, Ping Gong

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Review Article

Research progress on the mechanism of anti-myocardial infarction effect and clinical application of effective components of Salvia miltiorrhiza

Xin Zhang, Zhiying Bian, Jingyi Zhang, Liang Ding, Guiyun Cao, Lihao Zhu, Jing Li, Yuhong Liu

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Review Article

Rehmannia glutinosa polysaccharides: a review on structure-activity relationship and biological activity

Qianqian Cao, Zhixuan Wang, Youning Jiang, Chunhong Dong

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Original Research Article

Self-assembled amphiphilic bipyridine and bisquinoline cisplatin analogues: synthesis and anticancer properties

Gabriel A. Gonzalez, Javier Hernandez-Ortega, Sudakha Kalagara, Bonifacio Alvarado-Tenorio, Alejandro Martinez-Martinez, Angel G. Diaz-Sanchez, Juan C. Noveron

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Original Research Article

Synthesis and pharmacological evaluation of novel coumarin based triazolyl glycoconjugates as potential antibacterial and anti-proliferative agents

Surendra Jatav, Ranjit Singh, Nishant Pandey, Pratibha Dwivedi, Jyoti, Monika Thakur, Sudhir Pratap Singh, Ranju Bansal, Bhuwan B. Mishra

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Original Research Article

Increased rigidity and bioisosteric replacement in the design, synthesis and preliminary evaluation of novel, functionalized 3,3-dialkyl-γ-butyrolactones as sigma-2 ligands

Benjamin E. Blass, Rong Gao, Kevin M. Blattner, John C. Gordon, Douglas A. Pippin, Daniel J. Canney

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Original Research Article

Indazole derivatives as selective inhibitors of butyrylcholinesterase with effective blood-brain-barrier permeability profile

Asuka Joy Tobuse, Christine Shing Wei Law, Chun Keng Thy, Jason Jonah James, Chin Fei Chee, Keng Yoon Yeong

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Original Research Article

Polyketides from Neohelicosporium griseum: structure assignment and bioactivity investigation

Lijuan Zhang, Jian Ma, Mingfei Yang, Tianming Zhao, Mei Yan Han, Dege Zheng, Ausana Mapook, Yongzhong Lu, Ruvishika S. Jayawardena

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Original Research Article

Identification of α-mangostin as a potent inhibitor of β-lactamase OXA-48

Wenhui Cheng, Yuejuan Zhang, Cheng Chen, Lei Gao, Yuwei Lv, Dian Yu, Bin Chen, Yi Wan

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Original Research Article

Synthesis of adamantane-monoterpene conjugates with 1,3,4-thiadiazol-2(3H)-imine linker and evaluation of their inhibitory activity against TDP1

Aldar A. Munkuev, Alexandra L. Zakharenko, Tatyana E. Kornienko, Nadezhda S. Dyrkheeva, Ekaterina S. Ilina, Evgeniy V. Suslov, Fatima Issa, Chigozie Achara, Jóhannes Reynisson, Konstantin P. Volcho, Nariman F. Salakhutdinov, Olga I. Lavrik

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