Med. Chem. Res. 2024, Vol 33, Iss 10

Medicinal Chemistry Research | 2024 | ?Volume 33, Issue 10, ?is now available online.

In this issue

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Review Article

Nafithromycin (MIQNAF?): ultramodern lactone ketolide designed to treat community acquired bacterial pneumonia (CABP)

Satish Bhawsar, Ravikumar Tadiparthi, Abhijeet K. Kayastha, Prasad Dixit, Laxmikant Pavase, Amit Mishra, Vijay Chavan, Satish Birajdar, Mohammad Shaikh, Ravindra Yeole, Sachin Bhagwat, Mahesh Patel

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Review Article

Targeting selective inhibitors of PARPs in drug discovery and development

Maolin Duan, Jing Gao, Jiajin Li, Xiaoli Huang, Yijiu Ren, Yang Li, Mengya Liao, Yiwen Zhang

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Review Article

A review of trilaciclib, a first-in-class cyclin-dependent kinase 4/6 inhibitor, for the management of metastatic small-cell lung cancer

Twinkle I. Patel, Jay N. Joshi, Alexander J. Valvezan, Matthew J. Moschitto

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Review Article

Anticancer potential of delphinidin and its derivatives: therapeutic and mechanistic insights

Shabnoor Iqbal, Timothy Omara, Ivan Kahwa, Usman Mir Khan

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Review Article

Dauricine: a review of natural observation, pharmacology, and pharmacokinetics

Tran Quang Hai, Nguyen Thi Huong, Ninh The Son

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Review Article

Extraction and purification, pharmacological action, synthesis and product development of salidroside: a review

Yaxiao Liu, Linwei Dan, Jiamei Tang, Zitong Yin, Longzhu Yang, Dongdong Zhang, Xiaomei Song, Wei Wang, Yuze Li

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Original Research Article

Synthesis and evaluation of 2-methylbenzothiazole derivatives as monoamine oxidase inhibitors

Maryké Shaw, Jacobus P. Petzer, Theunis T. Cloete, Anél Petzer

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Original Research Article

Characterization of Allium tuberosum Rottl. peptides with dual inhibitory activities against angiotensin I converting enzyme and dipeptidyl peptidase-IV

Nhung Thi Phuong Nong, Chia-Hui Lee, Jue-Liang Hsu

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Original Research Article

Facile access to novel furoyl-based amide retroisoster inhibitors of LuxR-regulated quorum sensing: conformation analysis and docking studies

Laurent Soulère, Yves Queneau

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Original Research Article

Design and discovery of monopolar spindle kinase 1 (MPS1/TTK) inhibitors by computational approaches

Nan Li, Jianning Wang, Haiyue Wu, Zhichao Zheng, Wei Liu, Zijian Qin

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Original Research Article

Synthesis and evaluation of novel biaryl oxazolidinones effective against gram-positive bacterial infections

Satish Bhawsar, Mohammad Shaikh, Sanjeev Joshi, Amit Mishra, Laxmikant Pavase, Vijay Chavan, Amol Kale, Abhijeet K. Kayastha, Ravindra Yeole, Sachin Bhagwat, Mahesh Patel

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Original Research Article

Structural optimization and biological evaluation of quinoline/naphthalene-based glyoxalase-I inhibitors as anti-cancer candidates

Buthina A. Al-Oudat, Bushra S. Abu Al fool, Suaad A. Audat, Nizar A. Al-Shar’i, Qosay A. Al-Balas, Aref Zayed, Amanda Bryant-Friedrich

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Original Research Article

Exploration of potential antihypertensive peptides derived from farmed Chinese giant salamander (Andrias davidianus)

Chi-Wei Lee, Christoper Caesar Yudho Sutopo, Jong-Yuan Lee, Yu-Kuo Chen, Jue-Liang Hsu

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Original Research Article

Design, synthesis, anti-tubercular activity, and computational studies of novel 3-(quinolin-3-yl)-1-phenylprop-2-en-1-one derivatives

Neeru Bhanwala, Niranjana Sri Sundaramoorthy, Sirisha Gollapudi, Anita Sharma, Ramandeep Singh, Gopal L. Khatik

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Original Research Article

Design, synthesis and evaluation of imidazo[1,2-a]pyrazin-8(7H)-one derivatives as acetylcholinesterase inhibitors and antioxidants

Wen-Rong Du, Ben-Ben Wei, Xin-Yuan Guo, Yong Lan, Pan-Pan Shang, Yi-Xuan Wang, Xue-Wei Zhou, Xiao-Ke Wang, Zheng-Yue Ma

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Original Research Article

Synthesis and antiproliferative activity of 7-substituted amide estradiol derivatives

Chun-Fang Gan, Ying Li, Hua-Long Chen, Jia-Wei Yao, Yun-Qiong Gu, Bin Su, Zhi-Wei Zhong, Jian-Guo Cui, Yan-Min Huang, Zhi-Ping Liu

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Original Research Article

Design, synthesis and evaluation of sesamol-derived acetamides as dual inhibitors of monoamine oxidases and cholinesterases

Sandeep Kumar, Rangan Mitra, Senthil Raja Ayyannan

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Correction

Correction: Substituted furan-carboxamide and Schiff base derivatives as potential hypolipidemic compounds: evaluation in Triton WR-1339 hyperlipidemic rat model

Buthaina Hussein, Mohammad Alwahsh, Yusuf Al-Hiari, Laurance Bourghli, Basmah Al-Jammal, Tareq Al-Qirim, Nader R. AlBujuq, Rania Abu-zaid, Fadi G. Saqallah, Lama Hamadneh

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