Med. Chem. Res. 2023, Vol 32, Iss 8

Med. Chem. Res. 2023, Vol 32, Iss 8

Medicinal Chemistry Research | 2023 | ?Volume 32, Issue 8, ?is now available online.

In this issue

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Review Article

Recent insights into antibacterial potential of benzothiazole derivatives

Priyanka Kashyap, Sangeeta Verma, Pankaj Gupta, Rakesh Narang, Sukhbir Lal, Manish Devgun

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Review Article

Pks 13 inhibitors—a promising target for future antitubercular agents

Naga Tejaswi Uppumavuluri, Sri Ram Krovvidi, Raghu Prasad Mailavaram, Sujit Kumar Mohanty, Pran Kishore Deb, Katharigatta N. Venugopala

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Review Article

Structural classification of EZH2 inhibitors and prospects for the treatment of tumor: a review

Ling Yu, Ming-tao Xia, You-de Wang, Zhi-wei Yan, Li-ying Zhang, Shuai Li

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Review Article

From the ethnomedicinal plants in northern Indochina to the development of novel anti-cancer therapeutic agents

Mattapong Kulaphisit, Rachan Pangnuchar, Chalermpong Saenjum, Jiraprapa Wipasa, Pathrapol Lithanatudom

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Review Article

A review on reported phytochemicals as druggable leads with antimalarial potential

Avishek Guchait, Asim Kumar, Roopam Singh, Gaurav Joshi, Ashish Ranjan Dwivedi

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Original Article

Garcidepsidone B from Garcinia parvifolia: antimicrobial activities of the medicinal plants from East and North Kalimantan against dental caries and periodontal disease pathogen

Saat Egra, Harlinda Kuspradini, Irawan Wijaya Kusuma, Irmanida Batubara, Kosei Yamauchi, Tohru Mitsunaga

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Original Article

Antiproliferative effect, cell cycle arrest and apoptosis generation of novel 6-substituted N5-formyltetrahydropyrido[3,2-d]pyrimidine derivatives

Chonghui Gao, Mengmeng Yuan, Wei Jiang, Rongrong Wang, Baoyan Zheng, Junyi Liu, Zhili Zhang, Chao Tian, Meng Wang

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Original Article

Design, synthesis, and antitumor activity evaluation of carbazole derivatives with potent HDAC inhibitory activity

Likun Sun, Leiqiang Han, Liang Zhang, Chen Chen, Chengyun Zheng

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Original Article

Design, synthesis, and antiproliferative activities of novel thiazolyl-pyrazole hybrid derivatives

Burak Kuzu, Ali Ergü?, Fuat Karaku?, Ege Arzuk

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Original Article

Novel indanone-chalcone esters with potential anti-Alzheimer effects designed using hybridization and bioisosteric replacement approaches

Fereshteh Azimian, Mohammad Shahrivar-Gargari, Teymour Vahedpour, Salar Hemmati, Mahrokh Dastmalchi, Tuba Tüylü Kü?ükk?l?n?, Siavoush Dastmalchi

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Original Article

Semi-synthesis of novel thebaine derivatives with low cytotoxicity and their antibacterial and antihemolytic properties

Zahra Hasanpour, Peyman Salehi, Atousa Aliahmadi, Mahdieh Hoseinpour, Hossein Behboodi, Dan Staerk, Morteza Bararjanian

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Original Research

Design of novel amidoxime ketolide core and an efficient synthesis of WCK 4763: for treatment of gram-positive pneumococci

Satish Bhavsar, Ravikumar Tadiparthi, Shivaji Pawar, Abhijeet K. Kayastha, Vijay Chavan, Ravindra Yeole, Prasad Deshpande, Sachin Bhagwat, Mahesh Patel

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Original Research

Synthesis and pharmacological evaluation of new disulfides linked to 1,2,4-triazole bearing urea moiety

Rui Tang, Haichuan Zhao, Shuai Zhang, Xiaojia Liu, Jinbiao Liu, Wei Li, Hongying Wang, Caiwen Li, Baoquan Chen

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Original Article

Design, synthesis and biological evaluation of novel hybrids of quinazoline derivatives and phenylsulfonylfuroxan as potential anti-tumor agents

Hao Wang, Lingling Chi, Fuqing Yu, Honglin Dai, Chao Gao, Xiaojie Si, Zhengjie Wang, Limin Liu, Peirong Zhao, Yingnan Zhu, Hongmin Liu, Qiurong Zhang

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Original Research

Synthesis, antiviral evaluation, molecular docking study and cytotoxicity of 5′-phosphorylated 1,2,3-triazolyl nucleoside analogues with thymine and 6-methyl uracil moieties

Bulat F. Garifullin, Dmitry A. Tatarinov, Olga V. Andreeva, Mayya G. Belenok, Irina Yu. Strobykina, Leysan R. Khabibulina, Anna V. Shepelina, Vladimir V. Zarubaev, Alexander V. Slita, Alexandrina S. Volobueva, Alexandra D. Voloshina, Anna P. Lyubina, Liliya E. Saifina, Vyacheslav E. Semenov, Vladimir E. Kataev

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Original Research

Carboxylated chalcones and related flavonoids as inhibitors of xanthine oxidase

Oleksandr L. Kobzar, Alona V. Tatarchuk, Galyna P. Mrug, Svitlana P. Bondarenko, Bohdan A. Demydchuk, Mykhaylo S. Frasinyuk, Andriy I. Vovk

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Original Research

New purine-triazole hybrids as potential anti-breast cancer agents: synthesis, antiproliferative activity, and ADMET in silico study

Natália Machado P. de O. Torres, Gabriele de A. Cardoso, Heveline Silva, Rossimiriam P. de Freitas, Rosemeire B. Alves

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Original Research

Design, synthesis and biological evaluation of novel 2,4,6-trisubstituted quinazoline derivatives as potential antitumor agents

Hao Wang, Tianci Wang, Lingling Chi, Fuqing Yu, Honglin Dai, Chao Gao, Xiaojie Si, Zhengjie Wang, Limin Liu, Peirong Zhao, Yingnan Zhu, Hongmin Liu, Qiurong Zhang

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